CRT-100.51 Clinical Outcome of Left Main Stem (LMS) Percutaneous Coronary Intervention (PCI) in a Large Non-surgical UK Center: A 5-Year Clinical Experience

Alaour, Bashir; Onwordi, Eunice; Khan, Asif; Dana, Ali

doi:10.1016/j.jcin.2018.01.052

Cited by 3 publications

(7 citation statements)

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“…3 The rate of perforations complicating ULMS interventions has been reported to be in the region of 1.2% from single-center experience. 4 However, the literature surrounding ULMS perforation, its predictors and likely outcomes are very limited.…”

Section: Introductionmentioning

confidence: 99%

“…Coronary perforation (CP) is a rare but serious complication of PCI which has been shown to have an incidence of ~0.4% of all procedures 3 . The rate of perforations complicating ULMS interventions has been reported to be in the region of 1.2% from single‐center experience 4 . However, the literature surrounding ULMS perforation, its predictors and likely outcomes are very limited.…”

Section: Introductionmentioning

confidence: 99%

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The impact of coronary perforation in percutaneous interventions involving the left main stem coronary artery in the United Kingdom 2007–2014: Insights from the British Cardiovascular Intervention Society database

Hussain

Protty

Gallagher

et al. 2020

Cathet Cardio Intervent

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Background: Percutaneous coronary intervention (PCI) is increasingly utilized for treatment of coronary disease involving the unprotected left main stem (ULMS). However, no studies to date have examined the outcomes of such interventions when complicated by coronary perforation (CP). Methods: Using the British Cardiovascular Intervention society (BCIS) database, data were analyzed on all ULMS-PCI procedures complicated by CP in England and Wales between 2007 and 2014. Multivariate logistic regressions were used to identify predictors of ULMS CP and to evaluate the association between this complication and outcomes. Results: During 10,373 ULMS-PCI procedures, CP occurred more frequently than in non-ULMS-PCI (0.9 vs. 0.4%, p < .001) with a stable annual incidence. Covariates associated with CP included number of stents used, female gender, use of rotational atherectomy and chronic total occlusion (CTO) intervention. Adjusted odds of adverse outcomes for ULMS-PCI complicated by CP were higher for peri-procedural complications including cardiogenic shock, tamponade, side-branch loss, DC cardioversion, in-hospital major bleeding, transfusion requirement, and peri-procedural myocardial infarction. There were also significantly increased odds for in-hospital major adverse cardiac events (MACCE, OR 8.961, 95% CI [4.902-16.383]) and 30-day mortality (OR 5.301, 95% CI [2.741-10.251]). Conclusions: CP is an infrequent event during ULMS-PCI and is predicted by female gender, rotational atherectomy, CTO interventions or number of stents used. CP was associated with significantly higher odds of mortality and morbidity, but at rates similar to previously published all-comer PCI complicated by CP.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The impact of coronary perforation in percutaneous interventions involving the left main stem coronary artery in the United Kingdom 2007–2014: Insights from the British Cardiovascular Intervention Society database

Hussain

Protty

Gallagher

et al. 2020

Cathet Cardio Intervent

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“…The reported 1‐year rate was 17%, and mainly driven by death. However, this particular part of data was derived from the hospital's electronic records and not from any nationwide registry; this could signify a possible underestimation of events as these patients might have ended up in another medical facility 4 …”

mentioning

confidence: 99%

“…In this issue of the Journal, Lee et al 3 have done an excellent job at accumulating extensive data of all the LMS PCI performed in their center over 5 years, and describe their clinical outcomes, which had no onsite cardiac surgery back‐up 4 . Extensive data (113 variables) on indications, procedural details including complications and outcomes up to 1‐year follow‐up were obtained retrospectively from their British Cardiovascular Intervention Society (BCIS) database and electronic patient records.…”

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confidence: 99%

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Is cardiac surgery backup required for left main stenting?

Khan

Dangas

2022

Cathet Cardio Intervent

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Key Points Although CABG is the gold standard treatment for left main disease, PCI is a suitable alternative based on several clinical studies. The high‐risk features of left main PCI due to technically challenging anatomy as well as unfavorable clinical factors, typically mandates a cardiothoracic surgery backup. Emerging registry data suggest left main PCI can be safely performed without on‐site surgical backup.

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Prevalence and Impact of High Bleeding Risk in Patients Undergoing Left Main Artery Disease PCI

Chiarito

Kini

Roumeliotis

et al. 2021

JACC: Cardiovascular Interventions

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CRT-100.51 Clinical Outcome of Left Main Stem (LMS) Percutaneous Coronary Intervention (PCI) in a Large Non-surgical UK Center: A 5-Year Clinical Experience

Cited by 3 publications

References 0 publications

The impact of coronary perforation in percutaneous interventions involving the left main stem coronary artery in the United Kingdom 2007–2014: Insights from the British Cardiovascular Intervention Society database

The impact of coronary perforation in percutaneous interventions involving the left main stem coronary artery in the United Kingdom 2007–2014: Insights from the British Cardiovascular Intervention Society database

Is cardiac surgery backup required for left main stenting?

Prevalence and Impact of High Bleeding Risk in Patients Undergoing Left Main Artery Disease PCI

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