1986
DOI: 10.2106/00004623-198668030-00015
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Crush injury to the lower limbs. Treatment of the local injury.

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Cited by 171 publications
(67 citation statements)
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“…3 Therefore, treatment preferably should be started as soon as possible, even at the site of catastrophe. 4,5 In our patients, preventive treatment against acute renal failure began relatively late. Therefore, a longer period of being trapped, severe muscle injury leading to compartment syndrome, and rhabdomyolysis seem to be responsible for the development of acute renal failure in these patients.…”
Section: Discussionmentioning
confidence: 86%
“…3 Therefore, treatment preferably should be started as soon as possible, even at the site of catastrophe. 4,5 In our patients, preventive treatment against acute renal failure began relatively late. Therefore, a longer period of being trapped, severe muscle injury leading to compartment syndrome, and rhabdomyolysis seem to be responsible for the development of acute renal failure in these patients.…”
Section: Discussionmentioning
confidence: 86%
“…Although the indications and specific circumstances around these procedures are unknown, some experts and organizations advise against guillotine amputations [19,25,47], fasciotomies for acute closed muscle-crush injury [39,48,49,53], and internal fixation [21,25] in disaster and war settings. In addition, the observed ratio of greater than one revision for every primary amputation suggests higher revision rates than those documented in the developed world (25%-30%) [11,28,59].…”
Section: Discussionmentioning
confidence: 99%
“…Alkalinization of the urine with sodium bicarbonate to prevent the development of ARF after crush injuries and rhabdomyolysis has been supported by numerous animal studies [63,69], case reports [25,53,[83][84][85], and retrospective clinical studies [50,53,84]. Bicarbonate assists in the creation of alkaline urine, which serves to decrease cast formation and lessen the direct toxic effects of myoglobin [63].…”
Section: Managementmentioning
confidence: 99%
“…They went on to state that the excision of noninfected, necrotic tissue is not essential and may delay healing. Reis and Michaelson [85] had to perform above-knee amputations for uncontrolled sepsis in three of six patients who previously had undergone fasciotomies more than 24 hours after injury. They concluded that the sequelae of infection in a crushed extremity are much worse than the late muscle contracture that may result from fibrosis of muscle.…”
Section: Treatment Of Compartment Syndromementioning
confidence: 99%