Crustacean Color-Change Hormone: Amino Acid Sequence and Chemical Synthesis

Fernlund, Per; Josefsson, Lars

doi:10.1126/science.177.4044.173

Cited by 318 publications

(69 citation statements)

References 18 publications

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“…The octapeptide RPCH (pGlu-Leu-Asn-Phe-Ser-Pro-Gly-Trp-NH 2 ) was the first invertebrate neuropeptide fully structurally elucidated from eyestalk extracts of Pandalus borealis (143). It shares common features with the insect adipokinetic hormone (AKH) peptide family, viz.…”

Section: Red Pigment Concentrating Hormone (Rpch)mentioning

confidence: 99%

Circadian clocks in crustaceans: identified neuronal and cellular systems

Strauß

Dircksen²

2010

Front Biosci

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Circadian rhythms are known for locomotory and reproductive behaviours, and the functioning of sensory organs, nervous structures, metabolism and developmental processes. The mechanisms and cellular bases of control are mainly inferred from circadian phenomenologies, ablation experiments and pharmacological approaches. Cellular systems for regulation summarised here comprise the retina, the eyestalk neuroendocrine X-organ-sinus gland system, several neuropeptides such as red pigment concentrating, hyperglycaemic and pigment-dispersing hormones, and factors such as serotonin and melatonin. No master clock has been identified, but a model of distributed clockwork involves oscillators such as the retinular cells, neurosecretory systems in the optic lobes, putative brain pacemakers, and the caudal photoreceptor. Extraretinal brain photoreceptors mediate entrainment. Comparative analyses of clock neurons and proteins known from insects may allow the identification of candidate clock neurons in crustaceans as putative homologues in the two taxa. Evidence for the existence of "insect-like" intracellular clock proteins and (light sensitive) transcription factors is scarce, but clock-, period-, and cryptochrome-gene products have been localised in the CNS and other organs rendering further investigations into crustacean clockwork very promising.

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Section: Red Pigment Concentrating Hormone (Rpch)mentioning

confidence: 99%

Circadian clocks in crustaceans: identified neuronal and cellular systems

Strauß

Dircksen²

2010

Front Biosci

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“…To date, red pigment concentrating hormone (RPCH) and pigment dispersing hormone (PDH), which are produced by and released from the X-organ/sinus gland complex in the eyestalk, are well known as chromatophore-regulating neuropeptides (Keller 1992). RPCH was first isolated and sequenced from the pink shrimp Pandalus borealis (Fernlund and Josefsson 1972). This molecule is an octapeptide with an amidated C-terminus, and was the first neuropeptide to be characterized not only in crustaceans but also in invertebrates.…”

Section: Introductionmentioning

confidence: 99%

Crustacean Peptide Hormones: Structure, Gene Expression and Function

Katayama¹,

Ohira²,

Nagasawa³

2013

Aqua-BioSci. Monogr. (ABSM)

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Keywords AbstractHomeostasis, growth and reproduction in crustaceans are under endocrine control as is established in other animals. The identification of crustacean hormones and elucidation of mechanisms of hormonal regulation have been pursued extensively. Mechanisms are found to be partly similar to, but also considerably different from those in insects, although both groups of animals are arthropods. Molting in insects, for example, is positively regulated by prothoracicotropic hormone (PTTH), which is secreted by the brain/ corpora allata complex and stimulates the prothoracic glands to promote the synthesis and secretion of ecdysteroids. On the other hand, molting in crustaceans is negatively regulated by molt-inhibiting hormone (MIH), which is secreted by the X-organ/sinus gland complex and suppresses the Y-organs from synthesizing ecdysteroids during the intermolt period. Therefore, it is rather difficult to fully elucidate physiological mechanisms in crustaceans based only on the results obtained in insects. Using experimental evidence, we have thus far looked into the roles of crustacean eyestalk hormones and androgenic gland hormone (AGH). Various eyestalk hormones have been isolated from the sinus glands and characterized: e.g., crustacean hyperglycemic hormone (CHH), MIH, vitellogenesis-inhibiting hormone (VIH), red pigment concentrating hormone (RPCH) and pigment dispersing hormone (PDH). CHH, MIH and VIH are structurally similar, forming the CHH-family. Insects also possess molecules similar to CHH, RPCH and PDH, but their functions are different. In addition, AGH has been studied mainly using terrestrial isopods. Here, we describe the present state of our understanding of the structure and function of these peptide hormones, and discuss future perspectives. mercial importance in fisheries and aquaculture, while others play a key role as intermediates in the food chain, linking phytoplanktons and fishes within the aquatic ecosystem. Modern shrimp culture was first established in Japan over 50 years ago using the kuruma prawn Marsupenaeus (formerly Penaeus) japonicus, which is one of the most important commercial species in Japan, and the aquaculture technique has now spread to many countries, especially in tropical and subtropical

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“…Third, some insect species have two or three different AKHs whose functions are likely to be different, since they have slightly different physiological effects (Gade et al, 1994(Gade et al, , 1997Park and Keeley, 1998). Crustaceans contain only one member of the AKH/RPCH family, i.e., Panbo-RPCH, which was the first member of this family fully chemically characterized from a prawn (Fernlund and Josefsson, 1972). The same peptide was found in diverse species, ranging from prawns to crabs, crayfish, lobsters and spiny lobsters representing different infraorders and superfamilies (Gade, 2009), while in insects, the primary structures of 47 different forms of the family have been identified.…”

Section: Introductionmentioning

confidence: 99%

Immunolocalization of Two Putative Pigmentotropins Akh I and -MSH-Like Immunoreactivities in the Brain of Rough Woodlouse, Porcellio Scaber and Pill Bugs Armadillidium Vulgare (Crustacea, Isopoda).

Fouda

2013

Al-Azhar Bulletin of Science- Basic Science Sector

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Antisera against putative pigmentotropic neuropeptides, Adipokinetic hormone I (AKH I) and α-Melanocyte stimulating hormone (α-MSH) reacted with small sets of neurons in the cephalic ganglia of the isopoda Porcellio scaber and Armadillidium vulgare. The distributions of immunoreactivities resembled in the two species. AKH I-like immunoreactivity (AKH I-ir) occurs in both species. In P scaber 5 cells occurred in the optic lobe (OL) (3 small near Lamina ganglionaris, LG and 2 large dorsally) while in A.vulgare only one small cell near LG. The accessory lobe (AL) and subesophageal mass (SM) have the same pattern in both species. There are 2 cells in AL and 6 cells in SM (in the cells of mandibular ganglion,CMD). α-MSH immunoreactivity (α-MSH-ir) were located in OL, and SM in both species and in AL of A.vulgare. In P. scaber two large perikarya were located dorsally, one small ventrally, while in A.vulgare 4 large dorsally, one small ventrally and strong reactivity in pseudo-frontal organ (PFO). In AL, 3 immunopositive cells were observed. In SM 6 cells (4 in CMD, 2 in the cells of maxillulary ganglion, CML) in P scaber and 8 cells (6 in CMD, 2 in CML) were observed in A. vulgare. These results suggest the possible existence of AKH-like and α-MSHlike peptides in isopoda. No differences were detected between males and females. The projections of immunoreactive fibers were traced to several brain regions, the somatogastric nervous system and the neurohaemal organs, which suggest multiple functions of these peptides.

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Crustacean Color-Change Hormone: Amino Acid Sequence and Chemical Synthesis

Cited by 318 publications

References 18 publications

Circadian clocks in crustaceans: identified neuronal and cellular systems

Circadian clocks in crustaceans: identified neuronal and cellular systems

Crustacean Peptide Hormones: Structure, Gene Expression and Function

Immunolocalization of Two Putative Pigmentotropins Akh I and -MSH-Like Immunoreactivities in the Brain of Rough Woodlouse, Porcellio Scaber and Pill Bugs Armadillidium Vulgare (Crustacea, Isopoda).

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