Crustal fault zones provide interesting geological targets for high-temperature geothermal energy source in naturally deep-fractured basement areas. Field and laboratory studies have shown the ability of these systems to let fluid flow down to the brittle–ductile transition. However, several key questions about exploration still exist, in particular the fundamental effect of tectonic regimes on fluid flow in fractured basement domains. Based on poro-elasticity assumption, we considered an idealized 3D geometry and realistic physical properties. We examined a model with no tectonic regime (benchmark experiment) and a model with different tectonic regimes, namely a compressional, an extensional and a strike-slip tectonic regime. Compared to the benchmark experiment, the results demonstrate that different tectonic regimes cause pressure changes in the fault/basement system. The tectonic-induced pressure changes affect convective patterns, onset of convection as well as the spatial extent of thermal plumes and the intensity of temperature anomalies. Driven by poro-elastic forces, temperature anomalies around vertical faults in a strike-slip tectonic regime have a spatial extent that should be considered in preliminary exploratory phases.