The breakup of Pangea fundamentally shaped modern continents and controlled the climatic distribution and biodiversity on Earth. Although our knowledge on the processes that control the assembly and breakup of supercontinents has significantly improved, the timing of supercontinent assembly and breakup initiation remains in some cases controversial. According to the available data, the assembly of Pangea was completed in middle Permian time, resulting in the formation of major orogenic belts and transform faults like the N-S-trending, dextral, Caltepec fault in Mexico. Pangea breakup initiation is bracketed to early Middle Triassic time. In this work, we present new sedimentological, structural and U-Pb geochronological data from a fluvial unit, the Matzitzi Formation of southern Mexico, the age and tectonic setting of which have remained an enigma for the past century. Our data document that the Matzitzi Formation is the strati-EAGE MARTINI et al.