Cryo‐sectioning of mice for whole‐body imaging of drugs and metabolites with desorption electrospray ionization mass spectrometry imaging – a simplified approach

Abstract

DOI: Mass spectrometry imaging can be used for highly specific tracking of several compounds in one experiment. The cover shows mass spectrometry images of a mouse dosed intraperitoneally with the antidepressive drug amitriptyline. The signal from an endogenous lipid is displayed in green, the drug is illustrated in red, and one of the drug metabolites is indicated blue. For more details, see research article by Seda Okutan, Harald S. Hansen and Christian Janfelt on page 1633.

Future of Urological Diagnosis Using Proteomics: A Review of Literature

“…Mass Spectrometry [13] Electrospray Ionization [14] Matrix-Assisted Laser Desorption Ionization [15] Tandem Mass Spectrometry [16] Surface Enhanced Laser Desorption Ionization -Time of Flight Mass Spectrometry [15] …”