This paper presents an extensive characterization and modeling of a commercial 28-nm FDSOI CMOS process operating down to cryogenic temperatures. The important cryogenic phenomena influencing this technology are discussed. The low-temperature transfer characteristics including body-biasing are modeled over a wide temperature range (room temperature down to 4.2 K) using the design-oriented simplified-EKV model. The trends of the free-carrier mobilities versus temperature in long and short-narrow devices are extracted from dc measurements down to 1.4 K and 4.2 K respectively, using a recently-proposed method based on the output conductance. A cryogenic-temperature-induced mobility degradation is observed on long pMOS, leading to a maximum hole mobility around 77 K. This work sets the stage for preparing industrial design kits with physicsbased cryogenic compact models, a prerequisite for the successful co-integration of FDSOI CMOS circuits with silicon qubits operating at deep-cryogenic temperatures.The birth of CMOS-compatible qubits in silicon [1,2,3,4] has rebooted the interest in cryogenic CMOS electronics for computing applications. Since the 1970s, MOSFET devices have been under investigation at cryogenic temperatures for use in custom applications, such as low-noise scientific equipment, spacecraft, power conversion etc. [5,6,7,8,9]. However, despite its many benefits for reaching high-performance and low-power computing [10], cryogenic cooling did not stay into practice for computing, abandoning the trend set by the ETA-10 liquid-nitrogen-cooled supercomputer [11].Nowadays, co-integrating qubits and CMOS circuits on the same substrate can greatly aid the development of scalable quantum computers featuring massive parallelism and error correction [12,13,14]. In this context, a silicon-on-insulator (SOI) platform is particularly attractive since the back gate provides additional control over the electron-spin qubit, trapped under the front gate of a SOI (nanowire) MOSFET[12,15,16]. To integrate the control circuits with quantum devices working at deep-cryogenic temperatures, regular SOI MOSFETs need to demonstrate reliable digital, analog and RF functionalities at such low temperatures. Using SOI cryogenic control electronics, the back gate can prove a useful tool to control the threshold voltage and hence the power consumption in circuits integrated close to the qubits [17], benefiting qubit coherence time by lowering generated noise. The main focus is on advanced ultra-thin body fully-depleted SOI (FDSOI) technology, e.g., the 28-nm node, to enable ultimate scalability of the resulting hybrid quantum-classical system [16,18].The 28-nm node, presently considered the ideal node for analog and RF applications at room temperature [19], has recently been tested for digital and analog functionality down to liquid-helium temperature (4.2 K) [17], and millikelvin temperature (20 mK) [20]. The improvement in RF characteristics has been verified down to liquid-nitrogen temperature (77 K) [21]. In addition to device c...