Cryolipolysis for local fat reduction in adults from Brazil: A single‐arm intervention study

Abstract

Background Localized fat is a matter of great concern among individuals from today's society. Cryolipolysis is a noninvasive technique that have shown great results in reducing localized fat. Aims To analyze the efficacy of cryoplipolysis on visible local fat reduction in submental region, arms, or male breast (pseudogynecomastia) in Brazilian subjects, and to assess possible factors associated with treatment success. Methods Single‐arm, nonrandomized trial, with volunteers from both genders with visible excess fat in the arms or submental region or men presenting pseudogynecomastia. Eligible subjects were submitted to physical, photographic, and ultrasound analysis before and three months after intervention. A single cryolipolysis session was performed using specific methods for each region, followed by a local massage for two minutes. Data were described as measures of central tendency and dispersion and measures of frequency. Reduction in measurements and factors associated with treatment success was analyzed using appropriate statistical tests. Results Thirty‐six subjects underwent one session of cryolipolysis in each area (22 subjects treated the arms, 20 the submental region and 9 the breast). In general, a mean reduction of 19.1% was observed. Significant differences were observed for almost all body parts analyzed. Body mass index was the only variable showing a significant relationship with intervention results. Conclusions Cryolipolysis is a useful noninvasive tool in reduction of visible localized fat in arms and submental region and of pseudogynecomastia. Obese subjects are not benefited by the treatment.

Ultrasound assessment of abdominal adipose panniculus in patients treated with a single session of cryolipolysis in a clinical setting

“…However, despite the good safety profile of cryolipolysis, different mild and transient adverse events have been reported in different studies, including pain, erythema, mild swelling, scars, and numbness. 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 …”

“…However, despite the good safety profile of cryolipolysis, different mild and transient adverse events have been reported in different studies, including pain, erythema, mild swelling, scars, and numbness. [12][13][14][15][16][17][18][19][20] The main limitation of the current study is its retrospective design. Nevertheless, the strict nature of the inclusion/exclusion criteria and that fact that data have been evaluated in a masked fashion might have at least partially limited these drawbacks.…”

“…12,13 Cryolipolysis have been identified as a safe and effective treatment in clinical studies. 12,[14][15][16][17][18][19][20][21] Moreover, McKeown & Payne, 22 in a prospective study, published recently, evaluating the effectiveness of an intense CoolSculpting regime (multiple cycles/sessions), found significant improvements in body contouring, with a good safety profile. However, the question of whether a single session of cryolipolysis may significantly improve body contouring has not been fully elucidated.…”

“…Cryolipolysis have been identified as a safe and effective treatment in clinical studies. 12 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 …”

Noninvasive lipolysis modalities in aesthetic medicine

“…According to the evidence-based review above, cryolipolysis can be used in fat reduction of multiple body areas-thighs, flanks, upper arms, abdomen, lateral neck, and submental region. [12][13][14][15][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] It was also reported to be effective in the management of pseudogynecomastia in men. 16 Patient satisfaction was rated as high in the majority of included studies and ranged between 73% and 93%.…”