Cryoplasty for the Treatment of Coronary Bifurcation Stenoses Following Main Vessel Stenting

Abstract

In this first report of its use in the coronary circulation, cryoplasty for bifurcation side-branch disease was safe and associated with a low rate of clinical recurrence in carefully selected patients.

Cryoplasty for Canine Iliac Artery Stenosis and its Impact on Expression of TIMP-2 and MMP-2

“…[7][8][9] Recent clinical reports have shown that, compared with conventional balloon angioplasty, cryotherapy can significantly improve vascular patency by much as 79% to 82% within 1 year, while reducing the rate of stent use between 2.7% and 33%. 6,[10][11][12][13][14] However, cryotherapy's mechanism of action is not well understood. It may be related to reduced ECM synthesis, increased ECM degradation, induction of smooth muscle cell (SMC) apoptosis, and decreased proliferation and migration of SMCs.…”