Cryopreserved Amniotic Membrane for Modulation of Periodontal Soft Tissue Healing: A Pilot Study

Velez, Inés; Parker, William B.; Siegel, M.; Hernandez, Maria A.

doi:10.1902/jop.2010.100060

Cited by 42 publications

(42 citation statements)

References 13 publications

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“…Currently, there are some studies already released in the field of dentistry, either evaluating gingival wound epithelialization in rabbits healing after dental implant surgery 20 . In all cases, the amniotic membrane had a successful performance and it is seen as a safe technique to induce rapid epithelialization, collagen formation and for reducing inflammation, there by accelerating the healing process at soft and osseous tissue level.…”

Section: Discussionmentioning

confidence: 99%

Bone density of defects treated with lyophilized amniotic membrane versus collagen membrane: a tomographic and histomorfogenic study in rabbit´s femur

et al. 2014

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Abstract:The aim of this study was to compare bone density of bone defects treated with lyophilizated amniotic membrane (LAM) and collagen membrane (CM) at three and five weeks. Two bone defects of 4mm in diameter and 6mm deep were created in left distal femoral diaphysis of New Zealand rabbits (n=12). The animals were randomly divided into two groups. One of the defects was covered with lyophilized amniotic membrane (Rosa Chambergo Tissue Bank/National Institute of Child Health-IPEN, Lima, Peru) or collagen membrane (Dentium Co, Seoul, Korea). The second one was left uncovered (NC). The rabbits were killed after three and five weeks (three rabbits/period). The results showed a high bone density and defect repair by new bone. The tomographic study revealed that bone density of the defects treated with LAM at three weeks was equivalent to the density obtained with CM and higher density compared with NC (p<0.05). At five weeks, the bone density obtained with LAM was more than the density obtained with CM and NC (p<0.05). The histomorphometric study showed no significant differences between LAM and CM at three and five weeks (p>0.05). The results show that the lyophilizated amniotic membrane provides equal or higher bone density than the collagen membrane.

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Section: Discussionmentioning

confidence: 99%

Bone density of defects treated with lyophilized amniotic membrane versus collagen membrane: a tomographic and histomorfogenic study in rabbit´s femur

et al. 2014

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“…31,32 HAM is composed by a single epithelial layer, a thick basement membrane, and an avascular collagen layer. 29,33 These growth factors contribute to the anti-inflammatory, immunomodulatory, antimicrobial, antiviral, anti-scarring, and analgesic properties. 29,33 These growth factors contribute to the anti-inflammatory, immunomodulatory, antimicrobial, antiviral, anti-scarring, and analgesic properties.…”

Section: Human Amniotic Membranementioning

confidence: 99%

“…30,36 In periodontics, it has been investigated for application in guided tissue regeneration 36 and in the treatment of gingival recession. 29 Disadvantages of this allograft includes difficulty in handling, rapid degradation, and the lack of adherence in full-thickness burns where HAM acts as a temporary wound dressing. 29 Disadvantages of this allograft includes difficulty in handling, rapid degradation, and the lack of adherence in full-thickness burns where HAM acts as a temporary wound dressing.…”

Section: Human Amniotic Membranementioning

confidence: 99%

Extracellular matrix‐based scaffolding technologies for periodontal and peri‐implant soft tissue regeneration

Tavelli

McGuire

Zucchelli

et al. 2019

Journal of Periodontology

118

141

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The present article focuses on the properties and indications of scaffold‐based extracellular matrix (ECM) technologies as alternatives to autogenous soft tissue grafts for periodontal and peri‐implant plastic surgical reconstruction. The different processing methods for the creation of cell‐free constructs resulting in preservation of the extracellular matrices influence the characteristics and behavior of scaffolding biomaterials. The aim of this review is to discuss the properties, clinical application, and limitations of ECM‐based scaffold technologies in periodontal and peri‐implant soft tissue augmentation when used as alternatives to autogenous soft tissue grafts.

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“…[4] Recently, this multipurpose tissue has found application in the field of periodontics. Velez and co-workers[5] analyzed the effects of cryopreserved amniotic membrane (CAM) on periodontal soft tissue healing and observed that it was effective in helping cicatrization, wound healing, epithelization, facilitated migration and reinforced adhesion. Another report by Gurinsky[6] demonstrated that the processed allograft amnion may provide an effective alternative to autograft tissue in the treatment of recession defects.…”

Section: Introductionmentioning

confidence: 99%

Amnion membrane for coverage of gingival recession: A novel application

2014

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Introduction:Amnion allograft has been used in the field of medicine for its exceptional wound-modulating properties. However, in the field of dentistry, only a limited number of reports have explored its potential in healing of oral wounds.Materials and Methods:Amnion allograft in conjunction with coronally advanced flap has been used in the management of gingival recession.Results:A complete coverage along with excellent esthetics and an improvement in gingival biotype was observed at 6 months postoperatively.Discussion:Because of its inherent wound-modulating properties, amnion allograft may be used to enhance periodontal wound healing and enable tissue regeneration such as that in the coverage of gingival recession.Conclusion:Amnion allograft may provide an alternative to other conventional methods of treating gingival recession.

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Cryopreserved Amniotic Membrane for Modulation of Periodontal Soft Tissue Healing: A Pilot Study

Cited by 42 publications

References 13 publications

Bone density of defects treated with lyophilized amniotic membrane versus collagen membrane: a tomographic and histomorfogenic study in rabbit´s femur

Bone density of defects treated with lyophilized amniotic membrane versus collagen membrane: a tomographic and histomorfogenic study in rabbit´s femur

Extracellular matrix‐based scaffolding technologies for periodontal and peri‐implant soft tissue regeneration

Amnion membrane for coverage of gingival recession: A novel application

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