“…Nevertheless, not all patients will tolerate major palliative resectional surgery. Consequently, techniques such as electrocoagulation [10], cryotherapy [22], radiotherapy [14], endoscopic laser [10], and endoscopic transanal resection (ETAR) [2,23,30,33] have been used as alternatives to surgical treatment. ETAR, first described by Zinkin et al [33] in 1979, provides local control of the tumor and excellent palliation of symptoms, together with low morbidity and mortality [2,8,23,30,31,33].…”