Cryptorchidism in Animals and Man

Hobday, Frederick

doi:10.1177/003591572401701502

Cited by 10 publications

(3 citation statements)

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“…[3][4][5] As we all know, cryptorchidism is one of the risk factors of testicular cancer, with approximately 10% of testicular cancer occurring in this setting.- 1,2,5 Men with a previous history of cryptorchidism have a higher risk of suffering testicular cancers, which appears to be 5-10 times more common than in normal people. 2,6,7 To our knowledge, there were several studies [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] describing the relationship between cryptorchidism and testicular cancer, but no one reported whether cryptorchidism affects the clinical stage of testicular cancer.…”

Section: Introductionmentioning

confidence: 99%

<p>Evaluating the Effect of Cryptorchidism on Clinical Stage of Testicular Seminoma</p>

Wang¹,

Chen²,

Qiu³

et al. 2020

CMAR

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To study the effect of cryptorchidism on clinical stage (CS) of testicular seminoma (TS). Patients and Methods: In the Surveillance Epidemiology and End Results (SEER) database (2006)(2007)(2008)(2009)(2010)(2011)(2012)(2013)(2014)(2015)(2016), people with TS were enrolled in our research. Multivariable logistic regression models were constructed to compare the impact of cryptorchidism on CS. Results: This research was based on the registry information of 12,991 TS patients. All patients with a median age of 36 (13-107) years were pathologically diagnosed with orchiectomy or needle biopsy specimens. Patients with CS I, II, and III TS accounted for 70.68% (n = 9182), 8.30% (n = 1078), and 5.75% (n = 747) of all patients, respectively; still there were 15.27% (n = 1984) of patients whose CS could not be identified or was not available. Among all included patients, 43.45% (n = 5644) of them had normal testis, 2.93% (n = 272) had cryptorchidism, and the primary site of 54.46% (n = 7075) of patients' testis was unavailable. According to our study, patients with cryptorchidism were more likely to suffer advanced CS [OR=1.14, 95% CI (1.01-1.28), p=0.0407]. Furthermore, this effect became more remarkable after adjusting for other factors including age, region, marital status, race, year of diagnosis and laterality [OR=1.23, 95% CI (1.13-1.32), p<0.0001]. Conclusion:According to this study, TS patients with cryptorchidism would be at a higher risk of suffering advanced cancer than patients with normal testis. It demonstrates that surgical correction for cryptorchidism should be timely, and specific management should be conducted on this kind of TS patients.

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Section: Introductionmentioning

confidence: 99%

<p>Evaluating the Effect of Cryptorchidism on Clinical Stage of Testicular Seminoma</p>

Wang¹,

Chen²,

Qiu³

et al. 2020

CMAR

View full text Add to dashboard Cite

show abstract

“…They may be detected in the testicular parenchyma and epididymis of retained testes and, rarely, in the vaginal cavity of scrotal gonads, particularly in young horses. [1][2][3][4] It has been hypothesized that parasites reach the testis through the spermatic artery or directly from the peritoneum, moving under the tunica vaginalis of the testicular cord. 1,3,5 If the parasite dies in these aberrant districts, a granulomatous reaction develops, as demonstrated in the bull by an experimental infection of testes with dead larvae of Setaria labiatopapillosa.…”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3][4] It has been hypothesized that parasites reach the testis through the spermatic artery or directly from the peritoneum, moving under the tunica vaginalis of the testicular cord. 1,3,5 If the parasite dies in these aberrant districts, a granulomatous reaction develops, as demonstrated in the bull by an experimental infection of testes with dead larvae of Setaria labiatopapillosa. 6 Most infestations are not clinically manifested, with the exception of massive ones that cause an increase in testicular size.…”

Section: Introductionmentioning

confidence: 99%