Cryptosporidium diagnosed on endoscopic biopsy in a paediatric patient with inflammatory bowel disease

Cheung, Donna Ann; Langshaw, Amber; Rivera-Rivera, Edgardo

doi:10.1136/bcr-2017-222015

Cited by 3 publications

(1 citation statement)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Diagnosis of cryptosporidial enteritis is often missed on routine stool culture, ova and parasite tests due to the modified acid-fast stain (modified Ziehl-Neelsen or auramine) having a sensitivity of only 50% compared to enzyme immunoassay and direct fluorescent antibody methods that carry a sensitivity and specificity of >90% [7]. This holds true for our patient as her initial stool culture, ova and parasite tests did not uncover any Cryptosporidium spp.The convenient dot blot hybridization assay carries a sensitivity of 95% and a specificity of 99.7% [8].…”

Section: Discussionmentioning

confidence: 68%

An Unconventional Diagnostic Method for Cryptosporidial Enteritis in a Healthy Host: Never Call It Quits!

Amarnath

Imad

Ebare

et al. 2019

Case Rep Gastroenterol

View full text Add to dashboard Cite

Cryptosporidial enteritis has a rising incidence in the USA, mostly affecting immunocompromised individuals and children. It has a self-limiting course in healthy hosts. Herein, we present a unique case of a healthy middle-aged female who presented with a 1-month history of voluminous watery diarrhea and acute blood loss anemia. Cryptosporidial enteritis was diagnosed based on endoscopy with biopsy-proven evidence of 2 jejunal peptic ulcers infected with Cryptosporidium spp. that was originally missed on routine stool culture, ova and parasite tests. The patient was successfully treated with nitazoxanide, and eradication of the protozoan was also confirmed on repeat endoscopic biopsies of the ulcer that were carried out 6 months later. To our knowledge, this is the first case to be reported in the literature with infective colonization of peptic ulcers with Cryptosporidium spp. with consequent systemic symptoms.

show abstract

Section: Discussionmentioning

confidence: 68%

An Unconventional Diagnostic Method for Cryptosporidial Enteritis in a Healthy Host: Never Call It Quits!

Amarnath

Imad

Ebare

et al. 2019

Case Rep Gastroenterol

View full text Add to dashboard Cite

show abstract

Cryptosporidiosis in individuals with inflammatory bowel disease: a scoping review protocol

Liu,

Schnider,

DeArmond

et al. 2024

BMJ Open

View full text Add to dashboard Cite

IntroductionCryptosporidiosis is a leading cause of moderate-to-severe diarrhoea globally, and, while it is often self-limited, in immunocompromised individuals, the infection can be associated with significant morbidity and mortality. Diagnosis might be missed or delayed in patients with inflammatory bowel disease (IBD) due to similar presentation, and these patients may also be on immunosuppressive therapies, increasing their risk of infection. Additionally, gastrointestinal infection and dysbiosis may be a risk factor for IBD. Diagnosis, presentation and treatment of cryptosporidiosis in individuals with IBD, as well as any epidemiologic correlations between the two diseases, will be investigated.Methods and analysisMEDLINE, Embase, Cochrane Library, CINAHL, Dissertations and Theses Global and grey literature will be searched. Joanna Briggs Institute (JBI) methodology for scoping reviews was used for the protocol and will be for the review. Two reviewers will independently screen studies and extract data. The evidence and presentation of the results will be analysed with input from the review team. Studies of cryptosporidiosis in patients with IBD will be included. Paediatric, adolescent and adult studies in all patient environments will be included. Cases in which Crohn’s disease does not affect the intestine and cases in which cryptosporidial infection is not in the intestine will be excluded.Ethics and disseminationPublished clinical literature will be systematically reviewed, and this work does not directly involve patients. Consequently, ethical review by an institutional review board is not required. Data will be presented at academic conferences, and a culminating report will be published in a peer-reviewed journal.Open Science Framework registrationhttps://osf.io/j47mb.

show abstract

Saudi consensus guidance for the diagnosis and management of inflammatory bowel disease in children and adolescents

Saadah,

AlAmeel,

Al Sarkhy

et al. 2024

Saudi Journal of Gastroenterology

View full text Add to dashboard Cite

The management of inflammatory bowel disease (IBD) in children and adolescents is challenging. Clear evidence-based guidelines are required for this population. This article provides recommendations for managing IBD in Saudi children and adolescents aged 6–19 years, developed by the Saudi Ministry of Health in collaboration with the Saudi Society of Clinical Pharmacy and the Saudi Gastroenterology Association. All 57 guideline statements are based on the most up-to-date information for the diagnosis and management of pediatric IBD.

show abstract

Cryptosporidium diagnosed on endoscopic biopsy in a paediatric patient with inflammatory bowel disease

Cited by 3 publications

References 3 publications

An Unconventional Diagnostic Method for Cryptosporidial Enteritis in a Healthy Host: Never Call It Quits!

An Unconventional Diagnostic Method for Cryptosporidial Enteritis in a Healthy Host: Never Call It Quits!

Cryptosporidiosis in individuals with inflammatory bowel disease: a scoping review protocol

Saudi consensus guidance for the diagnosis and management of inflammatory bowel disease in children and adolescents

Contact Info

Product

Resources

About