“…Walter Hamilton, an attendee, offered to provide the first home for what is now known as the Protein Data Bank (PDB) [7]. The PDB was launched at Brookhaven National Laboratory, based on the Protein Structure Library created by Edgar Meyer [8]. The initial PDB archive contained fewer than ten structures, all of which were determined by X-ray crystallography.…”
The global Protein Data Bank (PDB) was the first open-access digital archive in biology. The history and evolution of the PDB are described, together with the ways in which molecular structural biology data and information are collected, curated, validated, archived, and disseminated by the members of the Worldwide Protein Data Bank organization (wwPDB; http://wwpdb.org). Particular emphasis is placed on the role of community in establishing the standards and policies by which the PDB archive is managed day-to-day.
“…Walter Hamilton, an attendee, offered to provide the first home for what is now known as the Protein Data Bank (PDB) [7]. The PDB was launched at Brookhaven National Laboratory, based on the Protein Structure Library created by Edgar Meyer [8]. The initial PDB archive contained fewer than ten structures, all of which were determined by X-ray crystallography.…”
The global Protein Data Bank (PDB) was the first open-access digital archive in biology. The history and evolution of the PDB are described, together with the ways in which molecular structural biology data and information are collected, curated, validated, archived, and disseminated by the members of the Worldwide Protein Data Bank organization (wwPDB; http://wwpdb.org). Particular emphasis is placed on the role of community in establishing the standards and policies by which the PDB archive is managed day-to-day.
“…Today, color graphics workstations make highly complex biological molecules comprehensible for teaching and research. Initially, the BRAD system triggered the formation of the Protein Data Bank (PDB) and CRYSNET. − 1 Depicts early (1968) 3-D color raster graphics from the BRAD 1 system using red-green stereo separation 2 Presents the illustration of the BRAD 1 3-D graphics for patent application S-36,382 by D. Ophir, B. J. Shepherd, and R. J. Spinrad.…”
mentioning
confidence: 99%
“…An opportunity presented itself to use a network link over a distance (College Station, TX − Brookhaven, NY) of 3000 km on the first Monday (sixth) of September, 1971, to demonstrate 29 program SEARCH to the Brookhaven host, the late Dr. Walter Hamilton. As a direct result of this demonstration, a proposal was submitted to and funded by the U.S. National Science Foundation to create CRYSNET, , which linked the Fox Chase Cancer Institute (PA) and Texas A&M with Brookhaven in a star-type network with 3-D graphics 44 capability. By 1974 two other institutions (Johns Hopkins University, MD, and the Medical Foundation of Buffalo, NY) had joined CRYSNET, and asynchronous communication with a variety of computers (CDC 7600, IBM 360/91, DEC PDP-10) was achieved.…”
mentioning
confidence: 99%
“…Initially, the BRAD system triggered the formation of the Protein Data Bank (PDB) 2 and CRYSNET. [3][4][5] While mathematicians and physicists enjoyed early access to computers, chemists tended to proceed at their own pace to make use of available computational resources. The field (i.e., hardware, software, and the user community) had to mature some before it was ready to create networks or link remote users.…”
The history of computer networking goes back 40 years. With few exceptions (e.g., libraries), the U.S.
Government established a creative environment or directly supported early developments. Chemical
networking goes back to the year 1971, when three groups virtually simultaneously initiated access to chemical
and structural databases.
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