Crystal and molecular structure analysis of 4-o-(4-methoxybenzoyl)-2-methyl-N-(2-pyridal)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide from laboratory X-ray powder data

Abstract

4-o-(4-methoxybenzoyl)-2-methyl-N-(2-pyridal)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide, C23H19N3O6S (I), a piroxicam derivative has been synthesized and characterized by X-ray powder structure analysis. The molecules of (I) are linked through pairs of intermolecular N–H···O and C–H···O hydrogen bonds forming centrosymmetric dimeric R 2 2(14)(M) and R 2 2(22)(N) rings which combine to form infinite one-dimensional MNMN… chain along the [2¯11] direction. The C–H···π (arene) hydrogen bonds interlink the parallel chains into two-dimensional sheets lying in the (102) plane. These sheets are further connected through intermolecular C–H···O and C–H···N bonds, so generating a three-dimensional framework structure in (I).