Crystal and molecular structure of chloroglycyl-dl-methioninatopalladium(II) monohydrate and its interaction with guanosine, cytidine and cytosine

New insights into the palladium-mediated selective hydrolysis of the His18–Thr19 peptide bond in cytochrome c: 1H NMR and density functional theory investigation for model compounds

“…2 shows, Pd(II) is coordinated in a square-planar configuration and a typical hydrogen bond between the protonated N p atom of imidazole and the carbonyl oxygen of glycine is kept, similar to the free tripeptide cation. Compared with X-ray crystallographic analysis results, 43 the calculated Pd-S distance is 0.16 A ˚longer and the Pd-N distance is similar. As shown in Table 2, the coordination of Pd(II) to the carbonyl oxygen of histidine lengthens the C=O bond but shortens the C-N bond distance due to p electron donation from nitrogen to carbon.…”

Transition metal complexes with oligopeptides: single crystals and crystal structures

“…57 However, in the presence of coordinating side chain residues, such as M 58 or H, 59 the O C atom is replaced by a S T or a N Im , increasing the stability of the complex. This is observed, for example, in [Pd(GM)]Cl (28), 60 [Pd(GH)Cl] (29) 61,62 or [Pd(GGH)] (30), 63 where Pd 2+ is coordinated by N A , N P and S T or N δ Im , respectively. The fourth position is occupied by a Cl − atom in the dipeptide complexes and by a N P atom in the tripeptide one.…”

Gold(III) and palladium(II) complexes of glycylglycyl-L-histidine: crystal structures of [AuIII(Gly-Gly-L-His-H−2)]Cl ·H2O and [PdII(Gly-Gly-L-His-H−2)] ·1.5H2O and HisɛNH deprotonation

“…the gold() complex, the deviations from the least-squares plane through Au, N(0), N(1), N(2) and N(34) calculated from the equation 0.681 (36)x ϩ 7.916 (22)y Ϫ 9.815(44)z = 0.182 (11) are very small: 0.003(6) Å for N(0), Ϫ0.006(7) Å for N(1), 0.004(6) Å for N(2), Ϫ0.005(5) Å for N(34) and 0.004(4) Å for Au. The root-mean-square deviation of the atoms from the fitted plane is 0.005 Å.…”

“…8 The only crystal structure of a copper() peptide is that of tri-α-aminoisobutyric acid, 9 a derivative of trialanine with two methyl groups attached to the α-carbon. Palladium()-peptide complexes have been widely studied and the available crystal structures are for complexes of glycyl--tyrosine and cytidine, 10 glycyl--methionine 11 and glycyl--histidine. 12 The only peptide crystal structures of platinum() are of glycyl--methionine 13 and diglycine 14 complexes.…”