Crystal Structure and Bioactivity of Complex [Gd(C₁₀H₉N₂O₄)(C₁₀H₈N₂O₄)(H₂O) ₃]₂·phen·4H₂O

Abstract

A novel gadolinium(III) complex with N-(2-propionic acid)-salicyloyl hydrazone (C 10 H 10 N 2 O 4 , H 3 L) and 1,10-phenanthroline (C 12 H 8 N 2 , phen) was prepared and characterized. The crystal structure of [Gd(H 2 L)(HL)-(H 2 O) 3 ] 2 •phen•4H 2 O was determined by X-ray single crystal diffractometry. The crystal complex crystallizes in the triclinic system with space group P-1. There are two 9-coordinated structure units in every complex molecule, in which Gd(III) is coordinated by two tridentate ligands (H 2 L and HL forms) and three water molecules and both the structural units take a distorted monocapped square antiprism. There is a free 1,10-phenanthroline connecting with coordinated water by hydrogen bonds in the crystal. The bioactivity tests indicate that the complex is an inhibitor against three bacteria.

Synthesis, characterization and structural studies of diorganotin(IV) complexes with Schiff base ligand salicylaldehyde isonicotinylhydrazone

“…In the IR spectra of ligand, the stretching vibration bands of N-H, O-H and C@O appear at 3415, 3255 and 1716 cm À1 , respectively [9], which disappear from the spectra of the complexes 1-8. The disappearance of v O-H shows the deprotonation of the -OH and its subsequent coordination to the center tin atom.…”

“…The Schiff base H 2 SalN has been prepared according to the literature for another salicylaldehyde-derived analogue salicylaldehyde salicylhydrazone [9]. An ethanol solution of salicylaldehyde (0.1 mol) was added slowly to an ethanol solution containing isonicotinyl hydrazide (0.1 mol) under stirring for 15 min, and the crude product was precipitated.…”

Synthesis, characterization and crystal structures of Ni(II), Cd(II) complexes withN-(2-propionic acid)-salicyloyl hydrazone and bipy/phen

“…Many of physiologically-active aroylhydrazone complexes find application in the treatment of diseases such as tuberculosis, tumor, cancer and insecticides [16][17][18][19][20][21]. Chelation therapy is the most successful means of treatment of heavy metal poisoning [22][23][24][25].…”