Crystal Structure and Superoxide Dismutase Activity of [Cu(Imidazole)₂(Quinoline)Cl₂]·0.5[Cu(Imidazole)₄Cl₂]

Cellulose Crystallites

“…The increased activity of the complexes can also be explained on the basis of their high solubility, fitness of the particles, size of the metal ion and the presence of the bulkier organic moieties. Formation of a hydrogen bond through the azomethine group with the active centre of cell constituents resultd in interference with the normal cell process 41. Another mechanism of toxicity of these complexes to microorganisms may be due to the inhibition of energy production or ATP production,42 by inhibiting respiration or by the uncoupling of oxidative phosphorylation.…”

Copper(II) complexes of hydroxyflavone derivatives as potential bioactive molecule to combat antioxidants: synthesis, characterization and pharmacological activities

“…Formation of a hydrogen bond through the azomethine group with the active centre of cell constituents resultd in interference with the normal cell process. [41] Another mechanism of toxicity of these complexes to microorganisms may be due to the inhibition of energy production or ATP production, [42] by inhibiting respiration or by the uncoupling of oxidative phosphorylation. The biological activity involves inhibition of DNA synthesis [43] by creating lesions in DNA strands by oxidative rupture and by binding the nitrogen bases or DNA or RNA, hindering or blocking base replication.…”

Copper(II) complexes with substituted imidazole and chlorido ligands: X-ray, UV–Vis, magnetic and EPR studies and chemotherapeutic potential

“…Structural features of copper(II) complexes with imidazole ligands were studied both in the solid state and in solution [14,[30][31][32][33][34][35][36][37][38][39][40][41][42][43][44]. It was found that the central copper(II) ion is usually surrounded by four imidazole ligands and typical coordination number in complexes with imidazole ligand is five or six.…”