Crystal structure of 1,1-diphenylethanol

In situ Crystallization Technique - an Approach to Circumvent Crystal Structures with high Z′-Crystallization Behavior of (CF3)2C-OH

“…Boese and Cirkel reported that the spatial requirements of the hydrophobic residue of (non‐fluorinated) alcohols are the dominating force in their crystal packing . The introduction of an additional methyl‐group like in 2‐methyl‐2‐propanol or sterically more demanding groups like in 1,1‐diphenyl‐ethanol leads to the formation of widened structures like tetramers or hexamers because of additional repulsive interactions. A similar behavior can be observed for the fluorinated counterparts of alcohols.…”

2,2,2-Triphenylethanol: a hydrogen-bonded tetramer based upon a centrosymmetric R44(8) motif

“…Although the dimers of Ph2(ferrocenyl)COH are formed by O--H...O hydrogen bonds giving fourmembered OHOH tings (Ferguson, Gallagher, Glidewell & Zakaria, 1993a), by contrast, in Ph2(PhCH2)COH the sole intermolecular interactions leading to dimer formation are O--H...Tr(arene) hydrogen bonds (Ferguson, Gallagher, Glidewell & Zakaria, 1994), while the dimers of Ph2(PhCHF)COH depend upon O--H...F hydrogen bonds (DesMarteau, Xu & Witz, 1992). The structure of Ph2(CH3)COH also contains O--H...Tr(arene) interactions, but these are intramolecular and the compound is monomeric (Sultanov, Shnulin & Mamedov, 1985b). In contrast to both Ph3COH and Ph2(PhCH2)COH, the introduction of further methylene spacer groups between the phenyl rings and the quaternary C atom in Ph(PhCH2)2COH and (PhCH2)3COH leads to structures which contain no hydrogen bonds (Ferguson, Gallagher, Glidewell & Zakaria, 1993b).…”

“…The compounds Ph3MOH (M = C, Si, Ge) all crystallize as hydrogen-bonded tetramers but while Ph3COH forms an almost perfectly tetrahedral tetramer (Ferguson, Gallagher, Glidewell, Low & Scrimgeour, 1992), the tetramers of both Ph3SiOH (Puff, Braun & Reuter, 1991) and Ph3GeOH (Ferguson, Gallagher, Murphy, Spalding, Glidewell & Holden,_1992) contain puckered O-atom tings of approximate 4 ($4) symmetry; Ph2(C2Hs)COH forms similar 4 tetramers (Sultanov, Shnulin & Mamedov, 1985a). Although the dimers of Ph2(ferrocenyl)COH are formed by O--H...O hydrogen bonds giving fourmembered OHOH tings (Ferguson, Gallagher, Glidewell & Zakaria, 1993a), by contrast, in Ph2(PhCH2)COH the sole intermolecular interactions leading to dimer formation are O--H...Tr(arene) hydrogen bonds (Ferguson, Gallagher, Glidewell & Zakaria, 1994), while the dimers of Ph2(PhCHF)COH depend upon O--H...F hydrogen bonds (DesMarteau, Xu & Witz, 1992).…”