Crystal structure of 1-benzyl-3-((4-bromophenyl)amino)-4-(4-methoxyphenyl)-1H-pyrrole-2,5-dione, C₂₄H₁₉BrN₂O₃

Abstract

CCDC no.: 1488220The asymmetric unit of the title crystal structure is shown in the figure. Atoms are shown with arbitrary radii. Tables 1 and 2 contain details on crystal structure and measurement conditions and a list of the atoms including atomic coordinates and displacement parameters. Source of materialA solution of p-methoxybenzoylformic acid (1.0 mmol), benzyl isocyanide (1.0 mmol), aniline (1.0 mmol) and ethyl glyoxylate (1.0 mmol) was stirred overnight in MeOH (2.0 mL) at room temperature. The reaction mixture was monitored by TLC. When no isonitrile was left, the solvent was removed under nitrogen blowing and the crude residue was dissolved in DIPA (2.0 equiv.) and DMF (3.0 mL). This solution was

Crystal structure of 4-benzyl-1-oxo-N-phenethyl-1H-[1,4]oxazino [4,3-b]indazole-3-carboxamide, C26H21N3O3

“…The Ugi three-component reaction (U-3CR), followed by various post-condensation transformations, is well known as a versatile and highly efficient synthetic strategy for the preparation of cyclic compounds [4,5]. We previously reported the use of this strategy to achieve the construction of various indazole compounds [6]. The asymmetric unit of the title compound contains one molecule.…”