Crystal structure of 2,2-dimethyl-5-(3,4,5-trimethoxybenzylidene)-1,3- dioxane-4,6-dione, C16H18O7

Abstract

Source of materialAmixture of malonic acid (3.08 g, 0.02 mol) and acetic acid anhydride (3 ml) in strong sulfuric acid (0.25 ml) was stirred with water at 303K. After dissolving, propan-2-one (1.16 g, 0.02 mol) was added dropwise into solution for 1h .The reaction was allowed to proceed for 2.5 h. Themixture was cooled and filtered, and then an ethanol solution of 3,4,5-trimethoxybenzaldehyde (6.36g,0.02 mol) was added. The solution was then filtered and concentrated. Single crystals were obtained by evaporation of an petroleumether-acetone (1:1 v/v)solutionof(I) at room temperature over aperiod of several days.

Crystal structure of 5-[4-(diethylamino)benzylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione

“…Several 5-arylidene-2,2-dimethyl-1,3-dioxane-4,6-diones (Huck et al, 1995;Gould et al, 1998;Novoa de Armas et al, 2000;O'Leary et al, 2001;O'Leary & Wallis 2006;Crawford & McNab, 2009;Wilsily & Fillion, 2009;Zeng, 2010aZeng, ,b, 2011aZeng, ,b,c, 2013Jie, 2012;García-Á lvarez et al, 2013;Dey et al, 2015) and their spiro-analogues (Sato et al, 1989;Zeng, 2011d,e,f; Zeng et al 2013) have been characterized by X-ray analysis. However, information on the crystal structure of 5-arylmethylidene-2,2-dimethyl-1,3-dioxane-4,6-diones containing an amino functionality on the aromatic ring is not available.…”