Crystal structure of 4-chloro-2-methyl-6-(4-(trifluoromethoxy)phenyl)pyrimidine, C₁₂H₈ClF₃N₂O

Abstract

CCDC no.: 1474902The asymmetric unit of the title crystal structure is shown in the figure. Tables 1 and 2 contain details on crystal structure and measurement conditions and a list of the atoms including atomic coordinates and displacement parameters. Source of materialThe title compound suitable was obtained from: 4,6-dichloro-2-methylpyrimidine (100 mg, 0.61 mmol) and (4-(trifluoromethoxy)phenyl)boronic acid (189 mg, 0.92 mmol) in dioxane (2 mL), which were added to a solution of dichlorido-bis(triphenylphosphine)palladium(II) (17 mg, 0.024 mmol) and Cs 2 CO 3 2 M (1 mL, 2 mmol). The mixture was stirred at 80°C for 30 min. in a microwave reactor. The mixture was cooled to room temperature and extracted