Crystal structure of di-μ-chlorido-bis[chloridobis(1,2-dimethyl-5-nitro-1H-imidazole-κN ³)copper(II)] acetonitrile disolvate

Abstract

1,2-Dimethyl-5-nitro­imidazole (dimetridazole, dimet) reacts with copper(II) chloride to give dinuclear [Cu(dimet)2(μ-Cl)Cl]2, in which each copper moiety is coordinated to two dimet ligands in a trans arrangement.

Crystal structure of hexa-μ-chlorido-μ4-oxido-tetrakis{[1-(2-hydroxyethyl)-2-methyl-5-nitro-1H-imidazole-κN 3]copper(II)} containing short NO2...NO2 contacts

“…Despite the widespread use of MET as a drug, relatively little structural data concerning its interactions with metal ions exist, and there are few structurally characterized copper compounds of MET (Galvá n-Tejada et al, 2002;Barba-Behrens et al, 1991;Athar et al, 2005;Ratajczak-Sitarz et al, 1998;Bharti et al, 2002). Our recent work has sought to develop further metal-MET chemistry and we have reported structures containing Cu Quinlivan & Upmacis, 2016), as well as Ag and Au (Quinlivan et al, 2015). Tetranuclear copper(II) compounds of the form [Cu 4 OX 6 L 4 ] are relatively well known, with the first example described in 1996 (Bertrand & Kelley, 1966).…”

Synergistically Enhanced Electrochemical Sensing of Food Adulterant in Milk Sample at Erbium Vanadate/Graphitic Carbon Nitride Composite

“…While the United States, Canada, Japan, and China have already banned DMZ, the United States and the European Union have also established a maximum residue limit of biological samples such as meat and milk. Among different biological matrices, milk has a lower maximum residue limit, and the detection limit is required to be ≤2 μg/kg [ 1 , 2 , 3 , 4 , 5 ].…”

Profoundly improved photostability of dimetronidazole by cocrystallization

“…Dimetronidazole (1,2-dimethyl-5-nitroimidazole, Scheme 1a, DMZ) 1 is an antibacterial and antiprotozoal veterinary drug for treating anaerobic and protozoal infections, e.g., chicken trichomonad, 2 bovine trichomoniasis, swine treponema hyodysenteriae and anaerobion. 3,4 DMZ has been banned as a prophylactic veterinary drug in China, some EU countries, and some North American countries for safety reasons. However, it is still used in some countries, including Australia, Canada and Denmark, for treating infections in food animals.…”