Crystal structure of (E)-5-((4-chlorophenyl)diazenyl)-2-(5-(4-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)-4-methylthiazole, C₂₃H₁₇ClFN₅S₂

Synthesis and Characterization of Novel 2-(1,2,3-Triazol-4-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazoles and 2-(4,5-Dihydro-1H-pyrazol-1-yl)-4-(1H-1,2,3-triazol-4-yl)thiazoles

“…Triazolylthiazoles can be produced from the cyclization of Schiff bases containing a triazole moiety in the presence of mercaptoacetic acids, or from carbohydrazides containing thiazole units and isothiocyanates or carbon disulfides, followed by cyclization and elimination of hydrogen sulfide [28]. Recently, we have reported the synthesis and crystal structures of novel heterocycles containing thiazole, pyrazoline, and 1,2,4-triazole moieties [29][30][31] as part of our long-term interest in new biologically active heterocycles [32][33][34]. In the current work, we report the synthesis of 2-(1,2,3-triazol-4-yl)-4,5-dihydro-1H-pyrazol-1-yl)thiazoles and 2-(4,5-dihydro-1H-pyrazol-1-yl)-4-(1H-1,2,3-triazol-4-yl)thiazoles using simple procedures and their structure characterization.…”