“…12,13) The existence of invertebrate lysozyme was first reported by Jollès and Jollès in 1975, 14) and the complete structure was first determined for marine bivalve Venerupis philippinarum lysozyme (VPL), to be composed of 123 amino acids (13.8 kDa) of a size similar to that of c-type lysozyme. 12,[15][16][17] In addition, several lysozymes have been identified in shellfish, including ones from coastal bivalves belonging to the genus Mytilus, 18,19) freshwater bivalve mollusk, 20) sea bivalves belonging to the genera Bathymodiolus and Calyptogena, [21][22][23] and a bivalve belonging to Chlamys islandica. 24,25) Furthermore, lysozymes from the starfish Asterias ruben, 26) Eisenia andrei, 27) Hirudo medicinalis, 28,29) and Stichopus japonicas 30) have also been reported.…”