Crystallisation kinetics of lactose in the presence of lactose phosphate

Crystallisation Kinetics of Ultra Pure Lactose

“…Fixing n at 2.8, the value previously obtained for ultra pure lactose (Lifran et al 2005), different values of K were found for ultra-pure and commercial lactose feeds. The growth rate constant K was higher for the ultra pure feed than for the commercial feed (Table 1).…”

“…A previous study established the kinetics of isothermal seeded batch crystallisation of ultrapure lactose in water, in the presence of LP (Lifran et al 2005). This study presents the results of seeded batch cooling crystallisations of both ultra-pure lactose and PGα-L contaminated with LP.…”

Lactose Contaminant as Steroid Degradation Enhancer

“…Known contaminants of lactose are riboflavin, potassium chloride and lactose-phosphate (29). In literature riboflavin and potassium chloride are not known as reactive impurities or as enolization enhancers.…”

“…Pharmaceutical grade lactose is contaminated with 270 to 400ppm lactose phosphate (29). Lactose-phosphate is already present in milk (25,29,31) and is known as a natural crystallization growth retarder (25).…”

“…Lactose-phosphate is already present in milk (25,29,31) and is known as a natural crystallization growth retarder (25). Upon crystallization the lactose-phosphate is preferentially integrated in the crystals in layers.…”