CSF oxytocin and vasopressin levels after recovery from bulimia nervosa and anorexia nervosa, bulimic subtype

Frank, Guido; Kaye, Walter H.; Altemus, Margaret; Greeno, Catherine G.

doi:10.1016/s0006-3223(00)00243-2

Cited by 52 publications

(32 citation statements)

References 20 publications

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“…However, it is not clear that these exogenous elevations of OT are related to differences in endogenous OT described here. There are several reports relating CSF and plasma levels of OT to human psychopathologies including OCD (Leckman et al, 1994), anorexia and depression (Frank et al, 2000), and Prader Willi syndrome (Martin et al, 1998). Differing basal levels and modulation of plasma OT levels have also been associated with differing levels of emotionality (Turner et al, 1999).…”

Section: Discussionmentioning

confidence: 99%

Rearing Effects on Cerebrospinal Fluid Oxytocin Concentration and Social Buffering in Rhesus Monkeys

Winslow

Noble

Lyons

et al. 2002

Neuropsychopharmacol

297

204

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Mother-reared (MR) and nursery-reared (NR) male rhesus monkeys exhibit profound and persistent differences in social and emotional behavior. Compared to MR animals, NR monkeys show reduced reciprocal social behaviors and increased agonistic behavior and high levels of stereotypy. Cerebrospinal fluid oxytocin (CSF OT) in NR monkeys was significantly reduced compared to MR monkeys measured at 18, 24, and 36 months of age. Correlations between OT and individual social behavioral profiles measured across rearing conditions also revealed a significant association between OT and the expression of affiliative social behaviors including allogrooming and reciprocal intermale mounting at each age examined. In contrast, CSF vasopressin levels did not differ according to rearing history, but did correlate with fearful behaviors independent of rearing history. Differential rearing was not associated with differences in basal or stressrelated plasma cortisol, although these levels did progressively decline as monkeys matured. MR but not NR monkeys were able to use a social companion to buffer their response to a stressor, but OT levels did not appear to be sensitive to the presence of a social companion in either group. These results are consistent with earlier reports from studies of rodents suggesting an important role for central OT pathways in the development of social affiliation.

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Section: Discussionmentioning

confidence: 99%

Rearing Effects on Cerebrospinal Fluid Oxytocin Concentration and Social Buffering in Rhesus Monkeys

Winslow

Noble

Lyons

et al. 2002

Neuropsychopharmacol

297

204

View full text Add to dashboard Cite

show abstract

“…Other factors such as fluid balance in the brain and the hormones that control it (vasopressin and naturitic hormone; Frank, Kaye, Altemus, & Greeno, 2000;Gold, Kaye, Robertson, & Ebert, 1983), brain tissue antibodies (Harel, Hallett, Riggs, Vaz, & Kiessling, 2001), and a host of gene products may be related to the changes seen in the starved brain. We hypothesize that of all these factors, IGF-1 and possibly IGF-2 may be the most promising factors controlling the brain tissue changes observed in starvation and refeeding.…”

Section: Discussionmentioning

confidence: 99%

Brain tissue volume segmentation in patients with anorexia nervosa before and after weight normalization

Swayze

Andersen

Andreasen

et al. 2002

Intl J Eating Disorders

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“…Corticotropin-releasing hormone (CRH) Gwirtsman et al (1983), Hotta et al (1986), Krahn and Gosnell (1989) Kaye et al (1982Kaye et al ( , 1987, , Waller et al (1986) Fullerton et al (1986, Baranowska (1990), Lesem et al (1991), Brambilla et al (1991), Brewerton et al (1992) CSF dynorphins Gerner and Yamada (1982), Kaye et al (1988), Pirke et al (1993), Baranowska et al (2000) Plasma SRIF ↓↑ → Plasma SRIF (response to test meal) ↑ Thyrotropin-releasing hormone (TRH) Devlin et al (1990), Lesem et al (1994) Gold et al (1983), Demitrack et al (1992), Chiodera et al (1993), Frank et al (2000) …”

Section: Central Peptides Modulating Eating Behaviour and Energy Homementioning

confidence: 99%

Central and Peripheral Peptides Regulating Eating Behaviour and Energy Homeostasis in Anorexia Nervosa and Bulimia Nervosa: A Literature Review

Tortorella

Brambilla

Fabrazzo

et al. 2014

Euro Eating Disorders Rev

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A large body of literature suggests the occurrence of a dysregulation in both central and peripheral modulators of appetite in patients with anorexia nervosa (AN) and bulimia nervosa (BN), but at the moment, the state or trait-dependent nature of those changes is far from being clear. It has been proposed, although not definitively proved, that peptide alterations, even when secondary to malnutrition and/or to aberrant eating behaviours, might contribute to the genesis and the maintenance of some symptomatic aspects of AN and BN, thus affecting the course and the prognosis of these disorders. This review focuses on the most significant literature studies that explored the physiology of those central and peripheral peptides, which have prominent effects on eating behaviour, body weight and energy homeostasis in patients with AN and BN. The relevance of peptide dysfunctions for the pathophysiology of eating disorders is critically discussed.

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CSF oxytocin and vasopressin levels after recovery from bulimia nervosa and anorexia nervosa, bulimic subtype

Cited by 52 publications

References 20 publications

Rearing Effects on Cerebrospinal Fluid Oxytocin Concentration and Social Buffering in Rhesus Monkeys

Rearing Effects on Cerebrospinal Fluid Oxytocin Concentration and Social Buffering in Rhesus Monkeys

Brain tissue volume segmentation in patients with anorexia nervosa before and after weight normalization

Central and Peripheral Peptides Regulating Eating Behaviour and Energy Homeostasis in Anorexia Nervosa and Bulimia Nervosa: A Literature Review

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