Csii

Ardilouze, Jean-Luc; Ménard, Julie; Gobeil, Fernand; Gagnon-Auger, Maude; Houde, Ghislaine; Pesant, Marie-Hélène; Rabasa‐Lhoret, Rémi; Baillargeon, Jean-Patrice

doi:10.1177/1932296815622647

Cited by 6 publications

(4 citation statements)

References 7 publications

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“…34 Other studies discuss the paucity of histological evidence and scarcity of tissue-material interaction. 3,7,17 A larger cross-sectional study on a pediatric population included a smaller subgroup for ultrasound analysis of CSII infusion sites compared with control regions and describes significantly increased echogenicity of the dermis and hypodermis compared with control regions. There were no reported differences in dermal thickness or vascularity.…”

Section: Resultsmentioning

confidence: 99%

“…Moreover, expectations of future research on better biocompatibility, fewer adverse events, and extended wear based on the material-tissue interaction in humans are justified. 3,7,8,21,30 People with diabetes must protect their skin real estate, which would lead to limited opportunities for biopsies and histological investigations in research on tissue-material interaction. Noninvasive techniques with conventional ultrasound and algorithm-assisted ultrasound have been used in IIS research for small sample sizes, but these and other techniques have yet to see applications on a larger scale.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, expectations of future research on better biocompatibility, fewer adverse events, and extended wear based on the material-tissue interaction in humans are justified. 3,7,8,21,30…”

Section: Discussionmentioning

confidence: 99%

“…An IIS catheter essentially infuses insulin from a pump reservoir to the subcutaneous space. 5,[7][8][9] CSII can be an alternative to MDIs and can result in good and reliable glycemic control. [10][11][12] Moreover, CSII enables patients to combine insulin infusion and glucose monitoring in a closed-loop feedback system, potentially improving glycemic control and quality of life.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Impact of Infusion Set Materials and Designs on the Subcutaneous Response in People With Diabetes: A Rapid Review of the Literature

Hendel¹,

Stumpe²,

Ozer³

2022

J Diabetes Sci Technol

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Insulin infusion sets (IISs) are an integral and intricate part of continuous subcutaneous insulin infusion for subjects with type 1 diabetes, infusing insulin from pump to the subcutaneous space. Insulin infusion sets interface with the skin surface, the dermis, and the subcutaneous space and may be the cause of infusion failure due to biological events or mechanical problems. Novel IISs with extended wear time and anti-inflammatory properties to mitigate these issues are described in the literature although material-tissue interactions are poorly understood. This rapid review focuses on the impact of IIS materials and designs on the subcutaneous response in people with diabetes and includes literature identified in PubMed, Embase, and Cochrane databases. Twenty-one studies were identified for qualitative synthesis that encompassed a limited and heterogenic body of evidence including 10 clinical reports, six reviews, one case report, two abstracts, and two communications. Two clinical reports were randomized crossover studies. Reports on materials mostly compared steel versus polytetrafluoroethylene (Teflon) cannulas and suggested no substantial difference in tissue response to these materials. Reports on designs focused mostly on the angle of cannula insertion. To drive and improve research on extended wear and nonimmunogenic IISs, future studies should focus on material-tissue interaction as dedicated outcome measures, quantified with punch biopsy and imaging techniques such as ultrasound, optical coherence tomography, and confocal reflectance microscopy. Original studies are required to further a field too young for a systematic meta-analysis.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Moreover, expectations of future research on better biocompatibility, fewer adverse events, and extended wear based on the material-tissue interaction in humans are justified. 3,7,8,21,30…”

Section: Discussionmentioning

confidence: 99%