CT-Derived Pulmonary Artery Diameters to Preselect for Echocardiography in COPD Patients Eligible for Bronchoscopic Treatments

Molen, Marieke C van der; Hartman, Jorine E.; Klooster, Karin; Kerstjens, Huib A. M.; Melle, Joost van; Willems, Tineke P.; Slebos, Dirk‐Jan

doi:10.1159/000509719

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…This could be explained by the relatively low prevalence of these comorbidities in comparison to other cohorts involving only patients with severe COPD [32,34]. This is in line with previous findings in a similar cohort as ours, herein only 1 out of 255 patients had systolic left ventricle dysfunction [35]. Diabetes and chronic kidney disease, with prevalences of 5% and 4% respectively, were also uncommon in our cohort [32].…”

Section: Discussionsupporting

confidence: 90%

Comorbidities reduce survival and quality of life in COPD with severe lung hyperinflation

ter Haar,

Slebos,

Klooster

et al. 2024

ERJ Open Res

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Rationale and aimPatients with chronic obstructive pulmonary disease (COPD) often present with a significant number of comorbidities, which are thought to be related to a higher mortality risk. Our aim was to investigate the prevalence and impact of comorbidities on survival and quality of life (QoL), specifically in patients with emphysema characterized by severe lung hyperinflation.Patients and methodsData were prospectively collected from patients, who visited our hospital for evaluating their eligibility for a bronchoscopic lung volume reduction treatment, and were included in the Groningen Severe COPD cohort (NCT04023409). Comorbidities were patient-reported by a questionnaire, and were validated with patients’ medical records. QoL was assessed with the St. Georges Respiratory Questionnaire (SGRQ).ResultsWe included 830 COPD patients with GOLD stage III and IV. The total number of comorbidities was an independent predictor of survival when adjusting for other factors influencing survival (HR 1.12, 95%CI:1.05–1.20, p<0.001). Of the individual comorbidities, pulmonary arterial hypertension (HR 1.53, 95%CI:1.01–2.32, p=0.045), low body-mass index (HR 1.63, 95%CI:1.16–2.27, p=0.004), and anxiety (HR 1.46, 95%CI:1.11–1.92, p=0.007) were independently associated with worse survival. Moreover, patients having 3, 4 or >5 comorbidities had a significantly (all p<0.05) worse QoL, in comparison to patients without comorbidities.ConclusionOur results show that comorbidities were associated with lower survival and poor QoL in emphysema patients characterized by severe hyperinflation. Appropriate treatment of treatable traits, including anxiety, low body-mass index, and pulmonary arterial hypertension, could lead to a survival benefit and improvement in QoL in this specific patient population.

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Section: Discussionsupporting

confidence: 90%

Comorbidities reduce survival and quality of life in COPD with severe lung hyperinflation

ter Haar,

Slebos,

Klooster

et al. 2024

ERJ Open Res

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“…In this study, only modest improvements in RVEDV were found in patients who had a signicant lung volume reduction (116.9 ml vs. 119.5 ml). However, echocardiography has been shown to be very challenging in patients with severe emphysema (29). Although all lung volume reduction methods resulted in increased end-diastolic volumes in these studies, a trend might be observed that larger reductions in lung volume tend to result in larger increases in RVEDVI and cardiac output based on our results and earlier studies.…”

Section: Discussionsupporting

confidence: 68%

Reduction of Lung Hyperinflation Improves Cardiac Preload, Contractility, and Output in Emphysema: A Clinical Trial in Patients Who Received Endobronchial Valves

Molen

Hartman

Vanfleteren

et al. 2022

Am J Respir Crit Care Med

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Rationale: Pulmonary hyperinflation in patients with chronic obstructive pulmonary disease has been related to smaller cardiac chamber sizes and impaired cardiac function. Currently, bronchoscopic lung volume reduction (BLVR) with endobronchial valves is a treatment option to reduce pulmonary hyperinflation in patients with severe emphysema. Conclusions:We found that reduction of hyperinflation using BLVR with endobronchial valves significantly improved cardiac preload, myocardial contractility, and cardiac output, without changes in pulmonary artery pressures.Clinical trial registered with www.clinicaltrials.gov (NCT03474471).

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“…Belief and attitude are motivation. Practice is the process of generating healthy behavior and eliminating harmful behavior [ 7 ]. The model of knowledge, belief, and practice was first reported in the 1980s in China.…”

Section: Introductionmentioning

confidence: 99%

Influence of Nurse-Led Health Education on Self-Management Ability, Satisfaction, and Compliance of Elderly Patients with Chronic Obstructive Pulmonary Disease Based on Knowledge, Belief, and Practice Model

Cao

et al. 2022

Computational and Mathematical Methods in Medicine

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Objective. Knowledge, belief, and behavior model (knowledge-attitude-practice (KAP)) is known as a cognitive model. Health education is important to the prognosis of patients, including chronic obstructive pulmonary disease (COPD) patients. However, the investigation regarding health education based on the KAP model is few. Thus, this work is aimed at analyzing the influence of nurse-led health education on self-management ability, satisfaction, and compliance of elderly patients with COPD based on knowledge, belief, and practice model. Methods. 60 elderly patients with COPD cured in our hospital from January 2019 to April 2021 were enrolled for the study. The patients were randomly assigned to control group ( n = 30 ) and study group ( n = 30 ). The former group received routine nursing, and the latter group accepted health education based on “knowledge, belief, and practice” model. Finally, the scores of nursing satisfaction, KAP score, compliance rate, self-management level, pulmonary function, and life quality were compared in the two groups. Results. The nursing satisfaction of the study group (100.00%) was higher than that (83.33%) of the control group ( P < 0.05 ). The scores of knowledge, attitude, and behavior were remarkably higher in the study group than in the control group after nursing ( P < 0.05 ). Moreover, KAP scores also significantly increased in the study group after nursing. The compliance rate of the study group (93.33%) was higher than that of the control group (66.67%) ( P < 0.05 ). After nursing, the scores of symptom management, daily life management, emotion management, information management, and management efficiency were higher in the study group than in the control group ( P < 0.05 ). In addition, pulmonary functions were improved in the two groups following nursing. Compared with the control groups, the 6 min walking distance, FEV1%, and FEV1/FVC% were higher in the study group ( P < 0.05 ). After nursing, the scores of life quality were reduced in the two groups. The scores of physiological function, psychological function, social function, and health self-cognition were lower in the study group than in the control group ( P < 0.05 ). Conclusion. Based on the model of knowledge, belief, and practice, nurse-led health education can successfully enhance the self-management ability, satisfaction, and compliance of elderly COPD patients.

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CT-Derived Pulmonary Artery Diameters to Preselect for Echocardiography in COPD Patients Eligible for Bronchoscopic Treatments

Cited by 3 publications

References 19 publications

Comorbidities reduce survival and quality of life in COPD with severe lung hyperinflation

Comorbidities reduce survival and quality of life in COPD with severe lung hyperinflation

Reduction of Lung Hyperinflation Improves Cardiac Preload, Contractility, and Output in Emphysema: A Clinical Trial in Patients Who Received Endobronchial Valves

Influence of Nurse-Led Health Education on Self-Management Ability, Satisfaction, and Compliance of Elderly Patients with Chronic Obstructive Pulmonary Disease Based on Knowledge, Belief, and Practice Model

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