CT detection of myocardial blood volume deficits: Dual-energy CT compared with single-energy CT spectra

Arnoldi, Elisabeth; Lee, Yeong Shyan; Ruzsics, Balázs; Weininger, Markus; Spears, J. Reid; Rowley, C.P.; Chiaramida, Salvatore A.; Costello, Philip; Reiser, Maximilian; Schoepf, U. Joseph

doi:10.1016/j.jcct.2011.10.007

Cited by 57 publications

(28 citation statements)

References 40 publications

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“…The source-oriented approach is the most widely studied and is based on a CT scanner equipped with two independent x-ray tubes and a set of detectors at an angular offset of 90-94 , with one tube operating at 80 or 100 kV and the other operating at 140 kV (23). The detectororiented approach that we hereby describe comprises a CT scanner with a single x-ray tube capable of rapid switching between 80 and 140 kV, hence shows promise to overcome some limitations of the source-oriented approach, such as increased scattered radiation and potential mismatch in the projection views between the high and low tube projections when scanning moving objects such as the heart.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Myocardial Perfusion Evaluation with Single Versus Dual-Energy CT and Effect of Beam-Hardening Artifacts

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Comparison of Myocardial Perfusion Evaluation with Single Versus Dual-Energy CT and Effect of Beam-Hardening Artifacts

et al. 2015

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“…However, discrimination is often limited by beam hardening artifacts, which mimic lower attenuating, nonviable tissue. Overlay of an iodine map or Z effective map onto attenuation images increases the sensitivity for detection of iodine distribution defects, including ischemia (24,25). The projection-based material decomposition employed to create these spectral results decreases beam hardening artifacts.…”

Section: Myocardial Perfusionmentioning

confidence: 99%

Spectral detector CT for cardiovascular applications

Rajiah¹,

Abbara²,

Halliburton³

2017

Diagn Interv Radiol

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In spectral computed tomography (CT), multiple spectrally distinct attenuation data sets are obtained from the same scan, which enables material composition analysis not possible with conventional CT. Dual-energy CT (DECT), where a low and high energy data set are obtained, is currently available in clinical practice using the following approaches: a) Dual source technology: two x-ray tube/detector systems separated by approximately 90 o and operated at different tube potentials (1) (Fig. 1a); b) Rapid tube potential switching technology: the potential applied across a single x-ray tube is switched rapidly between a high and low setting (1, 2) (Fig. 1b); c) Dual-spin technology: the same anatomical region is scanned twice during two consecutive rotations, once with a high potential applied across the x-ray tube and once with a low potential applied (1) (Fig. 1c); d) Split-beam technology: the spectrum emitted from a single tube is split into high and low energy spectra (3).Spectral detector CT (SDCT) (IQon, Philips Healthcare) is a novel technology introduced for clinical DECT data acquisition. A single potential is applied across a single x-ray tube and two layers of detectors separate low and high energy data: the top layer absorbs low energy photons and the bottom layer absorbs high energy photons (Fig. 1d). In addition to conventional (polyenergetic) images, projection data simultaneously obtained from both detector layers can also be utilized to generate spectral images. The spectral images useful for cardiovascular assessment include virtual monoenergetic images (Fig. 2a), iodine density maps (Fig. 2b), virtual unenhanced images (Fig. 2c), and effective atomic number (Z effective ) images (Fig. 2d). An important feature of SDCT technology is that spectral information is available in all patients without a priori selection of a special protocol or exposure to additional radiation. Images are available at full field-of-view and a minimum rotation time of 0.27 seconds (s) with complete temporal and spatial registration.In this paper, we present our initial clinical experience based on the acquisition of data from over 200 patients who underwent cardiovascular studies (i.e., cardiac, aorta, pulmonary veins, pulmonary arteries) using SDCT including the impact of this technology on radiation dose and contrast dose. The creation of spectral images from spectral data is discussed and the utility of these images is demonstrated for specific cardiovascular applications. 187From the Department of Radiology (P.R. ABSTRACTSpectral detector computed tomography (SDCT) is a novel technology that uses two layers of detectors to simultaneously collect low and high energy data. Spectral data is used to generate conventional polyenergetic images as well as dedicated spectral images including virtual monoenergetic and material composition (iodine-only, virtual unenhanced, effective atomic number) images. This paper provides an overview of SDCT technology and a description of some spectral image types. The potential utility o...

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“…Arnoldi et al were among the first to evaluate the diagnostic performance of DECT versus SECT for the detection of myocardial blood volume deficit, using SPECT as reference standard (72). Using a dual source scanner, DECT raw data was analyzed using: (I) high energy (140 kV), (II) low energy (80 or 100 kV), (III) mixed (30% low/70% high), and (IV) iodine maps.…”

Section: Clinical Evidence In Dectmentioning

confidence: 99%