CT Features of Pulmonary Mycobacterium avium Complex Infection

Lady Windermere syndrome

“…29,31 These individuals usually have nodular bronchiectasis with diffuse pulmonary involvement of 3-4 lobes; the right middle lobe and lingula are most commonly involved. 16,29,32 Bronchiectasis in the middle lobe and lingula is highly suggestive of MAC disease. 32,33 However, isolated middle lobe and lingular disease is a rare manifestation of nodular bronchiectasis even on early high resolution computed tomography (HRCT) scans.…”

“…16,29,32 Bronchiectasis in the middle lobe and lingula is highly suggestive of MAC disease. 32,33 However, isolated middle lobe and lingular disease is a rare manifestation of nodular bronchiectasis even on early high resolution computed tomography (HRCT) scans. 16 In the Reich and Johnson study only 6/29 patients originally examined had middle lobe and lingular involvement.…”

CT Findings of Mycobacterium Avium Intracellulare Infections in the Lung

“…The identification of multifocal coexistent bronchiectasis, air-space disease, and nodules at CT should raise the possibility of atypical mycobacterial lung disease, even in an otherwise healthy patient. The combination of multiple small nodules on CT with bronchiectasis, particularly in the middle lobe and/or lingual, should suggest the diagnosis (8,26,27).…”

“…In 1992 Reich et al (7) reported that MAI lung disease can present with a lingular and middle lobe pattern on chest radiography. Computed tomography (CT) studies of MAI lung disease have demonstrated nodular opacities and bronchiectasis with middle lobe and lingular bronchiectasis being suggestive of MAI lung disease (2,8,9). atypical mycobacterium most commonly associated with human disease.…”

Infection by Non Tuberculous Mycobacteria in Cystic Fibrosis

“…Cavities are finer and surrounded by less parenchymal opacification than in the case of tuberculosis (TB) (Erasmus et al, 1999). Bronchiectasis appear preferentially in the middle lobe and lingula (Lynch et al, 1995). Pleural effusion is not common.…”