CT findings at lupus mesenteric vasculitis

Ko, Sheung‐Fat; Lee, T.-Y.; Cheng, Tien‐Tsai; Ng, Shu Hang; Lai, Han; Cheng, Y.-F.; Tsai, Chung Chueng

doi:10.1080/02841859709171253

Cited by 86 publications

(42 citation statements)

References 16 publications

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“…Enhancing ascites, bowel thickening and halo/target signs were seen. A palisade or comb like pattern representing prominent vasculature supplying dilated bowel loops was concluded to be a potential early sign of disease [109]. Gas collection in the bowel and fat attenuation can also be seen on CT scan [106].…”

Section: Vasculitismentioning

confidence: 95%

The Gastrointestinal Manifestations of Systemic Lupus Erythematosus: A Survey of the Literature

Schulz¹,

Derk²

2009

TOAUTOJ

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Systemic Lupus Erythematosus (SLE) is an autoimmune disease associated with auto-antibody production and resulting widespread inflammation that has potential to affect and damage many organ systems. Gastrointestinal manifestations of SLE are well documented in the literature but the exact extent and frequency of their presence is likely grossly underestimated. Patients present with vague complaints such as abdominal pain and nausea with non-specific physical exam findings and inconclusive diagnostic tests and serologic analysis. Recent research has helped to better clarify these manifestations of SLE and has demonstrated distinct involvement of almost every portion of the GI tract. This article is based upon an exhaustive review of the literature from 1976 to present date and summarizes the major advances in the identification and differentiation of gastrointestinal incarnations related to systemic lupus erythematosus. The review also encompasses theories of etiology of the various manifestations, summarizes accepted and experimental treatment regimens, and highlights the differential diagnosis of each presented topic, including disorders of the oropharynx, esophagus, stomach, small and large intestine, liver and gallbladder and beyond.

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Section: Vasculitismentioning

confidence: 95%

The Gastrointestinal Manifestations of Systemic Lupus Erythematosus: A Survey of the Literature

Schulz¹,

Derk²

2009

TOAUTOJ

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“…The mesentery is often involved, with engorgement of mesenteric vessels Bcomb sign,^and increased attenuation of the mesenteric fat [3,45,46]. The area supplied by the superior mesenteric artery is preferentially affected [46], with the territory supplied by the inferior mesenteric artery also frequently involved [45]. Small bowel (jejunum, ileum) involvement is more frequent than large bowel, while gastric involvement is uncommon [47].…”

Section: Casementioning

confidence: 97%

“…CT findings can include focal or diffuse bowel wall thickening with target sign bowel dilatation and, rarely, pneumatosis intestinalis. The mesentery is often involved, with engorgement of mesenteric vessels Bcomb sign,^and increased attenuation of the mesenteric fat [3,45,46]. The area supplied by the superior mesenteric artery is preferentially affected [46], with the territory supplied by the inferior mesenteric artery also frequently involved [45].…”

Section: Casementioning

confidence: 97%

Mesenteric vasculitis in children with systemic lupus erythematosus

et al. 2015

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Lupus mesenteric vasculitis (LMV) is a severe and potentially fatal complication of systemic lupus erythematosus (SLE). Although LMV is always a consideration in adolescents and adult patients with SLE, who present with acute abdominal pain, diagnosis and management remain a great challenge. We describe the cases of five patients age 14 to 21 years old diagnosed with LMV. All five patients had active SLE and typical clinical presentation suspicious of LMV. Abdominal CT was the preferred imaging modality and was useful in four patients. Corticosteroids were the mainstay of treatment for all five patients. All five patients survived and complete remission of symptoms was achieved in four out of five patients with the addition of cyclophosphamide and in one out of five with rituximab. A review of the literature was performed including a systemic review of the case reports and case series published in the English literature over the last 20 years.

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“…Common CT findings in patients with LMV include dilated bowel, focal or diffuse bowel wall thickening, abnormal bowel wall enhancement (a double halo or target sign), mesenteric edema, engorgement of mesenteric vessels (comb sign), and ascites (Ko et al 1997;Ha et al 2000). It is usually multisegmental and not confined to a single vascular territory.…”

Section: Lupus Mesenteric Vasculitismentioning

confidence: 98%