CT findings in human fascioliasis

Miguel, Felipe de; Carrasco, José Ángel Gómez; Garcia, N.; Bustamante, Vı́ctor; Beltrán, Javier Benítez

doi:10.1007/bf01887824

Cited by 18 publications

(8 citation statements)

References 3 publications

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“…In addition, these lesions are arranged in a fashion of tortuous tract, which is quite unusual for usual pyogenic abscesses. We could find four reports of CT findings in hepatic fascioliasis with a total of 15 cases in the English literature [2][3][4]8]. These findings were similar to ours.…”

Section: Hepatic Lesions Caused By Fasciola Hepaticasupporting

confidence: 94%

“…The results of serologic tests are especially useful in the acute stage of the disease because there will be no eggs in bile juice or feces until the worm reaches the bile duct [2].…”

Section: Discussionmentioning

confidence: 99%

“…Unlike the usual clusters of microabscesses by pyogenic organisms which coalesce into a larger abscess cavity [9], hepatic lesions caused by Fasciola hepatica did not coalesce and evolved very slowly over several months. This difference might be caused by the fact that in fascioliasis, hepatic lesions are mainly coagulation necrosis [2][3][4] and not abscesses caused by infection. In addition, these lesions are arranged in a fashion of tortuous tract, which is quite unusual for usual pyogenic abscesses.…”

Section: Hepatic Lesions Caused By Fasciola Hepaticamentioning

confidence: 99%

“…Humans are accidentally infected by the ingestion of water or raw aquatic vegetables (usually watercress) contaminated with this metacercaria [1]. Numerous cases of hepatic fascioliasis have been reported in the medical literature; however, there are only a few reports of radiologic findings of human fascioliasis [2][3][4][5][6][7][8].…”

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confidence: 99%

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Radiological findings of human fascioliasis

et al. 1993

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Fasciola hepatica is a trematode of herbivorous mammals. Humans are accidentally infected by the ingestion of water or raw aquatic vegetables contaminated with the metacercaria. Radiological findings of six patients with fascioliasis (five hepatic fascioliasis, one biliary fascioliasis) were analyzed. The diagnosis was based on serological testing and/or histopathologic findings of eosinophilic abscess in five patients and identification of the adult worm in one patient. The characteristic radiological features of hepatic fascioliasis were (1) cluster of microabscesses arranged in tract-like fashion (burrow tract), (2) subcapsular location of the hepatic lesions, and (3) very slow evolution of the lesion on follow-up examinations. In biliary fascioliasis, there were multiple conglomerated filling defects in the common bile duct. The authors believe that the demonstration of these features, together with peripheral eosinophilia or eosinophilic aspirate from the hepatic lesion, is very helpful in making the correct diagnosis.

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Section: Hepatic Lesions Caused By Fasciola Hepaticasupporting

confidence: 94%

“…The results of serologic tests are especially useful in the acute stage of the disease because there will be no eggs in bile juice or feces until the worm reaches the bile duct [2].…”

Section: Discussionmentioning

confidence: 99%

Section: Hepatic Lesions Caused By Fasciola Hepaticamentioning

confidence: 99%

mentioning

confidence: 99%

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Radiological findings of human fascioliasis

et al. 1993

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“…4), duct dilatation and irregular wall thickening [61, 62]. CT can demonstrate peripheral tortuous lesions of the liver diagnostic of hepatic fascioliasis [63]. …”

Section: Hermaphroditic Trematode Infectionsmentioning

confidence: 99%

Biliary Parasites

et al. 1998

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Parasitic diseases of the biliary tract occur frequently in tropical and subtropical areas and cause high morbidity and mortality. In general, neither the clinical presentation nor the general laboratory findings are sufficiently unique to raise the possibility of a parasitic biliary infestation in the mind of the surgeon. Once considered, however, the presence of a parasitic biliary infestation is easily confirmed. Most commonly this is accomplished by the identification of the parasite in stools or duodenal contents. Ultrasonography, CT and MRI are not only important in the diagnosis of parasitic biliary diseases but also in the follow-up and surveillance. ERCP is an excellent diagnostic tool for demonstrating the presence of parasites in the biliary tree. Furthermore, ERCP is also used in the therapy of biliary parasitic infestations and carries less morbidity and mortality than the surgical approach. Surgery is only indicated in complicated cases. Mechanisms that may be effective against parasites include: antibodies; cytotoxic T cells; T-cell-induced activated macrophages; natural killer cells, and a variety of cells that mediate antibody-dependent cell-mediated cytotoxicity and modulators of the immune system such as cytokines. Future research has to focus on the importance of these mechanisms for the immune evasion by parasites.

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Successful treatment of acute fascioliasis with bithionol

Bacq

Besnier²,

Duong

et al. 1991

Hepatology

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Fascioliasis is the parasitic infestation of the liver and biliary tract related to Fasciola hepatica. Bithionol is proposed as the treatment of choice for human fascioliasis without major side effects. However, the efficacy of bithionol has been evaluated in chronic but not in acute fascioliasis. In this study we report on the success of treatment with bithionol in 10 patients with fascioliasis, 8 having acute fascioliasis. The criteria for the diagnosis of fascioliasis were hypereosinophilia, positive immunoelectrophoresis and indirect hemagglutination. Bithionol was given orally to hospitalized patients at the daily dose of 25 mg/kg body wt for 10 days. Three patients with acute fascioliasis received a second course of bithionol 2 or 3 mo after the first because of the recurrence of diarrhea and fatigue in one patient and persistent hypereosinophilia in two patients. All patients were cured. The follow-up period after the first course of treatment was between 16 and 47 mo. No major side effects were observed. We conclude that bithionol is the drug of choice for both acute and chronic fascioliasis. Moreover, its oral administration may allow treatment of fascioliasis in outpatients who do not have serious symptoms.

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CT findings in human fascioliasis

Abstract: Three patients with fascioliasis are presented in whom CT demonstrated abscesses and granulomas and permitted control of the disease's evolution after medical treatment.

Cited by 18 publications

References 3 publications

Radiological findings of human fascioliasis

Radiological findings of human fascioliasis

Biliary Parasites

Successful treatment of acute fascioliasis with bithionol

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