CT findings in <i>Pneumocystis carinii</i> pneumonia in five dogs

Schiborra, Frederike; Scudder, Christopher; Littler, Rebecca; Lamb, Chris; McConnell, J. Fraser; Maddox, Thomas W.

doi:10.1111/jsap.12833

Cited by 7 publications

(3 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hepatotoxicity is a known complication of TMS and has been reported with a variety of drug dosages and durations of treatment. 19 In dogs with Pneumocystis pneumonia, 8 to 12 weeks of treatment resulted in recovery when infection was identified promptly, 4 , 5 , 7 , 20 but less information is available in dogs with systemic pneumocystosis. Our report indicates that clinical signs of systemic pneumocystosis can be rapidly ameliorated by TMS administration, but monitoring for evidence of hepatotoxicity is essential.…”

Section: Discussionmentioning

confidence: 99%

Section: Metastatic Renal Calcification In Dog 1 Could Have Been Relatedmentioning

confidence: 99%

See 1 more Smart Citation

Oculosystemic pneumocystosis in 2 sibling Chihuahuas

Johnson

Hulsebosch

Viall

et al. 2023

Veterinary Internal Medicne

View full text Add to dashboard Cite

Sibling female and male Chihuahuas were evaluated for a 9-month history of tachypnea that failed to respond to fenbendazole, doxycycline, amoxicillin-clavulanate, and prednisone. Physical examination identified tachypnea, hyperpnea, and harsh bronchovesicular lung sounds. Fundic examination disclosed diffuse chorioretinitis, manifested as multifocal chorioretinal granulomas in the female dog and occasional chorioretinal scars in the male dog. Thoracic radiographs indicated moderate to severe interstitial to bronchointerstitial infiltrates in both dogs. Serum and urine antigen and antibody testing in the female dog failed to identify infectious agents, but cytologic assessment of hepatic lymph node, liver, and splenic aspirates identified Pneumocystis trophozoites. Infection was confirmed in both dogs by 28S rRNA PCR sequencing from multiple tissue samples.The female dog responded well to trimethoprim-sulfamethoxazole, but the male dog was euthanized because of liver failure, presumably related to antimicrobial treatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Metastatic Renal Calcification In Dog 1 Could Have Been Relatedmentioning

confidence: 99%

Oculosystemic pneumocystosis in 2 sibling Chihuahuas

Johnson

Hulsebosch

Viall

et al. 2023

Veterinary Internal Medicne

View full text Add to dashboard Cite

show abstract

“…Unlike the situation with P. jirovecii in humans, prevalence data for Pneumocystis in animal species is far less well documented. Canine cases of florid Pneumocystis pneumonia (PCP) have been fully described in only 53 dogs to date [ 13 , 14 , 15 , 16 , 17 , 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Pneumocystis Colonization in Dogs Is as in Humans

Danesi

Petini

Falcaro

et al. 2022

IJERPH

View full text Add to dashboard Cite

Pneumocystis is an atypical fungus that resides in the pulmonary parenchyma of many mammals, including humans and dogs. Immunocompetent human hosts are usually asymptomatically colonised or show subtle clinical signs, but some immunocompromised people can develop florid life-threatening Pneumocystis pneumonia (PCP). Since much less is known concerning Pneumocystis in dogs, we posit the question: can Pneumocystis colonization be present in dogs with inflammatory airway or lung disease caused by other pathogens or disease processes? In this study, Pneumocystis DNA was detected in bronchoalveolar lavage fluid (BALF) of 22/255 dogs (9%) with respiratory distress and/or chronic cough. Although young dogs (<1 year-of-age) and pedigree breeds were more often Pneumocystis-qPCR positive than older dogs and crossbreds, adult dogs with other infectious conditions and/or a history of therapy-resistant pulmonary disease could also be qPCR-positive, including two patients with suppression of the immune system. Absence of pathognomonic clinical or radiographic signs render it impossible to convincingly discriminate between overt PCP versus other lung/airway disease processes colonised by P. canis. It is possible that colonisation with P. canis might play a certain role as a co-pathogen in some canine patients with lower respiratory disease.

show abstract

Pneumocystosis

Lobetti¹,

Sykes²

2021

Greene's Infectious Diseases of the Dog and Cat

View full text Add to dashboard Cite

CT findings in Pneumocystis carinii pneumonia in five dogs

Cited by 7 publications

References 25 publications

Oculosystemic pneumocystosis in 2 sibling Chihuahuas

Oculosystemic pneumocystosis in 2 sibling Chihuahuas

Pneumocystis Colonization in Dogs Is as in Humans

Pneumocystosis

Contact Info

Product

Resources

About