CT Findings in Late-Onset Epilepsy

Sayette, Vincent de La; Cosgrove, Ryan; Melanson, Denis; Ethier, R

doi:10.1017/s0317167100026627

Cited by 14 publications

(5 citation statements)

References 10 publications

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“…4 de la Sayette et al, in a study on 387 patients over 50 years of age with late-onset epilepsy, reported that most patients for whom CT scan was performed had either normal results or evidence of cerebral atrophy. 9 In another study on children hospitalized due to afebrile seizure in Tehran, Iran, 90% of the CT scans were reported as normal, which is in accordance with our study. 10 On the other hand, Smith et al in 2013 studied 309 patients with their first-onset seizure in South Africa.…”

Section: Discussionsupporting

confidence: 91%

<p>Brain CT Findings in Patients with First-Onset Seizure Visiting the Emergency Department in Mashhad, Iran</p>

Zarmehri

Teimouri

Ebrahimipour

et al. 2020

OAEM

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Introduction: Regarding the complications and costs of CT imaging for patients, this study aimed at investigating the necessity of CT scans in patients visiting the emergency unit with first-onset seizure. Methods: One hundred patients who had experienced their first seizure were enrolled. Their CT scan was studied, and based on the radiology report, the type of probable pathologies and their percentage were determined. Results: The patient's mean age was 39.78±17.43 yrs. CT scan abnormalities were reported in 27 cases as follows: nonspecific senile changes in 11 (40.7%), encephalomalacia in 3 (11.1%), acute infarct in 5 (18.5%), lacunar infarct in 3 (11.1%), mass-like lesion in 4 (14.8%) and cerebral venous thrombosis (CVT) evidence in 1 (3.7%). Acute infarct and mass-like lesions were seen together in the CT scan of one patient. In only 9 of the 27 abnormal CT scans, the findings were in accordance with seizure consisting of an acute infarct, mass-like lesion, and CVT evidence. Discussion: It seems that performing a CT scan in all patients referring to the emergency department with a first-onset seizure is not necessary.

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Section: Discussionsupporting

confidence: 91%

<p>Brain CT Findings in Patients with First-Onset Seizure Visiting the Emergency Department in Mashhad, Iran</p>

Zarmehri

Teimouri

Ebrahimipour

et al. 2020

OAEM

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“…The direct admission of head injury cases to the neurosurgical department could be the reason behind this phenomenon, as it would make it difficult for us to observe posttraumatic immediate/early onset of epilepsy. Nonetheless, it is comparable to 4.10% cases in the Rochester, Minnesota study 8 In the present study, 28% cases were of idiopathic epilepsy, which is somewhat comparable to 35% in the study done by Rigatti M et al 6 and 44% in the study done by Pradeep P. V. et al 5 In the present study, generalized seizure was the most common seizure type with 58.67% cases while partial seizure was observed in 41.33% cases; which is comparable to 58.4% and 41.6% respectively in the study conducted by Lopez et al 11 In the present study, abnormal CT scan of brain was seen in 65.33% cases, which is comparable to 62% in the study done by De La Sayette V et al 12 and 72% in the study done by Medina et al 13…”

Section: Discussionsupporting

confidence: 82%

A study of etiological aspect of epilepsy in non-paediatric patients

Acharya

Chovatia

2016

Int J Adv Med

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Background: Epilepsy is a neurological condition characterized by the recurrence of paroxysmal episode of abnormal neuronal function. Epilepsy brings in undesirable social, psychological and economical consequences to its patients. In contrast to early onset of epilepsy in childhood, late onset of epilepsy is usually symptomatic; which usually responds well to antiepileptic drugs. Methods: A prospective study of 75 patients of late onset epilepsy was carried out to ascertain the etiology and to evaluate the usefulness of neuroimaging in late onset epilepsy. Results: We found that majority (72%) of patients of late onset epilepsy were male. About 65% of patients had abnormal CT scan-brain findings. Generalized seizure was the most common seizure type with about 59% cases. Conclusions: Generalized seizures are more common in idiopathic group of epilepsy whereas partial with or without secondary generalized seizures are more common in the symptomatic late onset epilepsy. The new neuroimaging techniques should be an integral part of investigation work up in all cases of epilepsy as they make it possible to find out the etiology in majority of cases. In late onset epilepsy, diagnostic usefulness of EEG is corroborative to CT and MRI.

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“…Cerebral vascular disease appears to be the most frequently identified cause of late-onset epilepsy, while cerebral neoplasms are uncommon. [9] In the present study, Tuberculoma was found to be present among in 18 patients with partial seizures. Cerebral infarct was found to be present in 10 patients with partial seizures and among 15 patients with generalized seizures.…”

Section: Original Articlesupporting

confidence: 50%