CT findings in sequel of COVID-19 pneumonia and its complications

Garg, Mandeep; Prabhakar, Nidhi; Bhatia, Harsimran; Dhooria, Sahajal; Debi, Uma; Muthu, Valliapan; Maralkunte, Muniraju; Sehgal, Inderpaul Singh; Agarwal, Ritesh; Sandhu,

doi:10.1259/bjro.20210055

Cited by 6 publications

(6 citation statements)

References 15 publications

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“…Atypical findings that were observed in our study include tree in bud opacities, "halo" sign, "Reverse halo" sign, and cavitation. These findings are in concordance with the previous studies published by Garg et al describing the pulmonary sequelae in COVID-19 patients in which they concluded that COVID-19 patients are more prone to develop superadded bacterial and fungal infections secondary to immunosuppression [16]. Similar to their results, two of our patients were found to have COVID Associated Pulmonary Mucormycosis and one patients had COVID associated Pulmonary Aspergillosis; while another two patients found to have spontaneous pneumomediastinum and four patients had pneumothorax which is in agreement with the previous reports published by Brogna et al [17].…”

Section: Discussionsupporting

confidence: 93%

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Role of Ct Chest in Evaluation of Pulmonary Manifestations of Covid-19 Recovered Cases

Aarti

Gupta

Sibia

et al. 2023

Asian J Pharm Clin Res

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Objective: Pulmonary manifestations may be seen in a number of coronavirus disease 2019 (COVID-19)-recovered the evidence on post-COVID pulmonary sequelae is still limited. Herein, we aim to assess the role of computed tomography (CT) chest in the evaluation of pulmonary manifestations of COVID-19 recovered cases. Methods: We conducted a hospital-based study in the Department of Radiodiagnosis at Government Medical College and Rajindra Hospital Patiala. It included 182 reverse transcriptase-polymerase chain reaction (RT-PCR)-proven COVID-19 patients after they recovered from the disease with at least one negative RT-PCR test and/or clinical recovery. Clinical data and CT findings in the recovery phase were summarized, and the relationship of different clinical parameters with CT severity scores was analyzed. Results: The mean (±standard deviation [SD]) age of patients was 50.2±14.7 years, and 62.6% of them were males. The mean (±SD) symptomatic-scan interval was 33.05±22.27 days. Pulmonary abnormalities were found in the majority of the cases in the recovery phase, that is, 176 patients accounting for 96.7%, while six patients had normal scans. Bilateral involvement was seen in 169 out of 176 patients. Common CT patterns observed were ground glass opacities (90.34%), reticular pattern (81.82%), interlobular septal thickening (70.45%), linear opacities (90.34% cases), fibrous stripes (78.41% cases), and consolidation (36.93%). The mean (±SD) CT severity score of our study subjects was 16.10±7.95. Patients were also categorized into four groups according to symptomatic scan interval <1 month, 1–2 month, 2–3 month, and >3 months. We found that residual changes were more severe in patients with shorter symptomatic scan interval. Conclusion: COVID-19 patients demonstrate persistent pulmonary abnormalities even after clinical recovery. Hence, follow-up in patients with moderate and severe disease is strongly recommended.

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Section: Discussionsupporting

confidence: 93%

“…The mean (±SD) CT severity score in our study population was 16.10±7.95. The median (IQR) CT severity score was 19 (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23).…”

Section: Ct Imaging Characteristicsmentioning

confidence: 99%

Role of Ct Chest in Evaluation of Pulmonary Manifestations of Covid-19 Recovered Cases

Aarti

Gupta

Sibia

et al. 2023

Asian J Pharm Clin Res

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“…Однако не удалось доказать связь с каким-то конкретным бактериальным или грибковым возбудителем, поскольку этот симптом при КТ обнаруживался у 100% пациентов с любой сопутствующей респираторной инфекцией. Таким образом, несмотря на наличие новых участков консолидации, полостных образований и бронхоэктазов, обычно свидетельствующих о наличии грибковых инфекций, следует учитывать, что и они не являются пато гномоничными [4,45].…”

Section: кт-признаки Covid-19 ассоциированного аспергиллеза легкихunclassified

“…Согласно опубликованным данным, у пациентов с COVID-19 признаки бронхиолита, которые проявляются утолщением стенок бронхов и/или появлением внутридольковых очагов и симптома "дерева с набухшими почками", являются признаками аспергиллеза дыхательных путей [56]. Так, наличие групп центрилобулярных очагов, перибронхиальных консолидаций и утолщения стенок бронхов может ассоциироваться с COVID-АЛ [45]. По наблюдениям E. Baratella и соавт., только у 1/ 9 пациентов с COVID-АЛ была "классическая" лучевая картина грибкового поражения в виде полостей или диффузных паренхиматозных узелков.…”

Section: кт-признаки Covid-19 ассоциированного аспергиллеза легкихunclassified

Possibilities of CT in the diagnosis of pulmonary aspergillosis in patients with COVID-19 (literature review)

Nay,

Yudin,

Abovich

2023

Medicinskaâ vizualizaciâ

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Aim: to analyze the latest research in the field of CT diagnostics of pulmonary aspergillosis in patients with COVID-19 according to domestic and foreign literature.Results. Pulmonary aspergillosis is one of the most common life-threatening fungal diseases that is caused by inhalation of Aspergillus mold spores and affects all parts of the respiratory system. In recent years, there has been a sharp increase in cases of invasive mycotic processes. During the COVID-19 pandemic, according to a number of authors, the incidence of pulmonary aspergillosis reached 34.4%, and the mortality rate was 74%. The World Health Organization calls for “minimizing the disproportionate use of corticosteroids and antibiotics for mild and moderate cases”. She explained that corticosteroids in severe cases do save lives, but their massive use can cause fungal infections. This complication is increasingly common in patients after corticosteroid and antibiotic therapy, with immunodeficiency states, as well as those treated in intensive care units. The COVID-19 pandemic has created additional challenges in the diagnosis, treatment and prevention of fungal complications. The clinical and radiographic features of fungal infections are largely similar to typical pulmonary manifestations of COVID-19. A comparative analysis of CT signs of various forms of pulmonary aspergillosis before and during the COVID-19 pandemic was carried out according to the literature. The main CT symptoms of mycotic lung lesions among patients who have undergone COVID-19 have been identified. Currently, computed tomography is crucial, first of all, to detect and monitor complications of COVID-19, including the addition of a secondary fungal infection.Conclusion. To make a conclusion about mycosis in the early stages, special vigilance and high qualification of the radiologist are required, which in turn will contribute to the timely appointment of antifungal therapy, which will reduce morbidity and mortality.

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“… 11 In addition, notable CT finding of pulmonary artery pseudoaneurysm has been reported in patients of pulmonary mucormycosis, both in cases with or without comorbid COVID-19. 12 , 14 …”

Section: Covid-19–associated Pulmonary Mucormycosismentioning

confidence: 99%

The Integral Role of Radiology in the Diagnosis and Management of COVID-19–Associated Mucormycosis Infections

Prabhakar

Garg

et al. 2022

The American Journal of Tropical Medicine and Hygiene

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Recently, there has been a sudden surge in COVID-19–associated mucormycosis (CAM) infections. Rhino-oculo-cerebral and pulmonary mucormycosis are the two most common forms of CAM. Radiology plays an integral role in the management of CAM. Computed tomography (CT) determines gross bony and soft tissue involvement in COVID-19–associated rhino-oculo-cerebral mucormycosis, whereas magnetic resonance imaging helps in evaluation of the orbital and intracranial extension. Paranasal sinus soft tissue with extrasinus infiltration with or without bony destruction is suggestive of COVID-19–associated rhino-oculo-cerebral mucormycosis. High-resolution CT chest scan has shown to be helpful in the diagnosis of COVID-19–associated pulmonary mucormycosis. Consolidation and cavitation are the most common imaging features. Other CT abnormalities include the reverse-halo sign, pleural effusion, ground-glass opacities, pneumothorax, nodules, and pulmonary embolism. A high index of suspicion with appropriate imaging findings can lead to the early diagnosis of CAM and timely initiation of antifungal treatment and/or surgical debridement, which can be lifesaving.

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CT findings in sequel of COVID-19 pneumonia and its complications

Cited by 6 publications

References 15 publications

Role of Ct Chest in Evaluation of Pulmonary Manifestations of Covid-19 Recovered Cases

Role of Ct Chest in Evaluation of Pulmonary Manifestations of Covid-19 Recovered Cases

Possibilities of CT in the diagnosis of pulmonary aspergillosis in patients with COVID-19 (literature review)

The Integral Role of Radiology in the Diagnosis and Management of COVID-19–Associated Mucormycosis Infections

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