CT findings in temporal bone sites in skull base osteomyelitis from malignant otitis externa

Brenner, Adi; Cavel, Oren; Shendler, Genady; Dekel, Michal; Handzel, Ophir; Eta, Rani Abu; Oron, Yahav; Muhanna, Nidal; Ungar, Omer J.

doi:10.1007/s00405-022-07749-1

Cited by 1 publication

(3 citation statements)

References 25 publications

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“…Surgical debridement may be required in severe cases or when there is a failure to respond to medical therapy. Overall, the management of NOE requires an aggressive and multidisciplinary approach, and even with optimal treatment, the condition carries a significant risk of morbidity and mortality 3 …”

Section: Introductionmentioning

confidence: 99%

“…Overall, the management of NOE requires an aggressive and multidisciplinary approach, and even with optimal treatment, the condition carries a significant risk of morbidity and mortality. 3 NOE represents therefore an underappreciated and complex disease, both from a diagnostic and from a therapeutic perspective. It potentially requires exploring several differential diagnoses and therefore represents an optimal benchmark for testing the capabilities offered in terms of clinical management by artificial intelligence (AI) tools.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Are artificial intelligence large language models a reliable tool for difficult differential diagnosis? An a posteriori analysis of a peculiar case of necrotizing otitis externa

Pugliese,

Maccari,

Felisati

et al. 2023

Clinical Case Reports

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Key Clinical MessageLarge language models have made artificial intelligence readily available to the general public and potentially have a role in healthcare; however, their use in difficult differential diagnosis is still limited, as demonstrated by a case of necrotizing otitis externa.AbstractThis case report presents a peculiar case of necrotizing otitis externa (NOE) with skull base involvement which proved diagnostically challenging. The initial patient presentation and the imaging performed on the 78‐year‐old patient suggested a neoplastic rhinopharyngeal lesion and only after several unsuccessful biopsies the patient was transferred to our unit. Upon re‐evaluation of the clinical picture, a clinical hypothesis of NOE with skull base erosion was made and confirmed by identifying Pseudomonas aeruginosa in biopsy specimens of skull base bone and external auditory canal skin. Upon diagnosis confirmation, the patient was treated with culture‐oriented long‐term antibiotics with complete resolution of the disease. Given the complex clinical presentation, we chose to submit a posteriori this NOE case to two large language models (LLM) to test their ability to handle difficult differential diagnoses. LLMs are easily approachable artificial intelligence tools that enable human‐like interaction with the user relying upon large information databases for analyzing queries. The LLMs of choice were ChatGPT‐3 and ChatGPT‐4 and they were requested to analyze the case being provided with only objective clinical and imaging data.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%