CT findings of adrenal schwannoma

Zhang, Y.-m.; Lei, Pengfei; Chen, M.-n.; Lv, Xiaofei; Ling, Yuye; Cai, Pei; Gao, Jian-ming

doi:10.1016/j.crad.2016.01.010

Cited by 35 publications

(24 citation statements)

References 44 publications

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“…They are usually unilateral, with slight contrast enhancement (7). Cystic changes and septa are key radiologic features of primary adrenal schwannomas (15). Magnetic resonance imaging is nonspecific 7, however, it may be helpful in the differential diagnosis of other solid nonfunctional tumors (14).…”

Section: Discussionmentioning

confidence: 99%

Adrenal Microcystic Reticular Schwannoma

Maciel¹,

Pereira²,

Simões³

et al. 2019

AACE Clinical Case Reports

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Objective: Schwannomas are usually benign tumors, originating from the Schwann cell myelin sheath around the peripheral or cranial nerves. Visceral schwannomas are rare, and less than 60 cases of adrenal schwannomas have been reported. Microcystic/reticular schwannoma (MRS) is the rarest variant of schwannoma and only 2 cases have been reported in the adrenal gland. Here we describe a third case. Methods: We describe a case of an adrenal MRS with a comprehensive literature review. Results: The patient was a 69-year-old, Caucasian female with abdominal pain. An abdominal computed tomography scan revealed a solid, lobulated, 78-mm mass of the left adrenal gland. Two inconclusive adrenal biopsies were performed and then she was referred to our tertiary center for further evaluation. No clinical or laboratorial signs of endocrine dysfunction were identified. A positron emission tomography scan with fluorodeoxyglucose showed a single left adrenal hypermetabolic mass (SUVmax = 71.7), suggestive of malignancy. In this context, an open left adrenalectomy was undertaken. The histologic evaluation showed an MRS. Conclusion: Adrenal MRSs are extremely rare tumors. Definitive diagnosis of schwannoma can only be made by surgical excision with histopathologic and immunohistochemical evaluation of the specimen.

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Section: Discussionmentioning

confidence: 99%

Adrenal Microcystic Reticular Schwannoma

Maciel¹,

Pereira²,

Simões³

et al. 2019

AACE Clinical Case Reports

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“…Compared with their counterparts arising in the head and neck or extremities, retroperitoneal schwannomas have a higher tendency to undergo spontaneous cystic degeneration . Cystic change is also the major feature of primary adrenal schwannoma, which usually can be detected on CT and MRI . In the present study, two types of intralesional cystic areas were found in the 11 cases, and a multiseptated cystic appearance was the most frequent form.…”

Section: Discussionmentioning

confidence: 43%

“…In the present study, two types of intralesional cystic areas were found in the 11 cases, and a multiseptated cystic appearance was the most frequent form. Although the appearance of cystic change on CT and MRI has been reported, this is the first detailed US description of the different forms of cystic change of adrenal schwannomas.…”

Section: Discussionmentioning

confidence: 90%

“…15 On MRI, adrenal schwannomas have been described as a mass with low signal intensity on T1-weighted images and heterogeneous high signal intensity on T2-weighted images. 15,22 US findings have only been addressed in a few case reports. 4,11,20 As previously reported, adrenal schwannoma usually appears as a well-demarcated, homogeneous, hypoechoic mass.…”

Section: Resultsmentioning

confidence: 99%

“…The usual CT appearance of adrenal schwannoma is that of a well‐defined unilateral mass with cystic degeneration, with a characteristic, progressive contrast‐enhanced pattern after contrast injection . On MRI, adrenal schwannomas have been described as a mass with low signal intensity on T1‐weighted images and heterogeneous high signal intensity on T2‐weighted images . US findings have only been addressed in a few case reports .…”

Section: Discussionmentioning

confidence: 99%

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Sonographic appearances of adrenal schwannomas

Zhou

Zhu

Zhang

et al. 2018

J of Clinical Ultrasound

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Objective To evaluate the sonographic ultrasound (US) appearances of adrenal gland schwannomas. Materials and Methods This was a retrospective analysis of 15 cases of schwannomas involving the adrenal gland. The following US features were assessed: size, border, echogenicity, homogeneity, intralesional cystic necrosis, presence of septa, intralesional calcification, posterior acoustic enhancement and blood supply. Results Of the 15 tumors, seven (46.7%) were located on the left side, and the remaining eight (53.3%) on the right side. The most frequent US appearance of adrenal schwannoma was a single, well‐defined and isoechoic mass. The internal echotexture was homogeneous in 2 cases, and heterogeneous in 13 cases, with intralesional cystic areas (n = 11), septa (n = 10) or calcifications (n = 6). Posterior acoustic enhancement was seen in 12 of the 15 cases (80%). On color Doppler US, 86.7% (13/15) of the lesions did not show any vascularity. Conclusions Adrenal schwannomas usually present on US as well‐defined isoechoic masses often with posterior acoustic enhancement, cystic necrosis with septa and poor blood supply. These appearances should suggest the diagnosis of adrenal schwannomas. Nevertheless, additional information from laboratory tests and CT or MR imaging may be required to avoid unnecessary surgery.

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Abdominal schwannomas: review of imaging findings and pathology

Lee

Hruban²,

Fishman

2017

Abdom Radiol

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Schwannomas are typically slow growing, encapsulated benign neoplasms. Visceral schwannomas are rare, and preoperative diagnosis is challenging, as they are often confused with other neoplasms even with advanced imaging studies. Surgical excision is usually needed to establish a definitive diagnosis, as pathology is the "gold standard." We review the imaging findings of abdominal schwannomas focusing on pancreatic, gastrointestinal, and retroperitoneal/adrenal schwannomas with pathology correlation. We conclude that schwannoma should be included in the broad differential diagnosis of an abdominal mass and that when it is unnecessary radical resection can be avoided.

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CT findings of adrenal schwannoma

Cited by 35 publications

References 44 publications

Adrenal Microcystic Reticular Schwannoma

Adrenal Microcystic Reticular Schwannoma

Sonographic appearances of adrenal schwannomas

Abdominal schwannomas: review of imaging findings and pathology

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