CT Findings of Endobronchial Metastasis

Ikezoe, Junpei; Johkoh, T.; Takeuchi, N.; Ishida, T.; Morimoto, S.; Kitamura, I.; Ohshima, M.; Kozuka, T.

doi:10.3109/02841859109177606

Cited by 20 publications

(10 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One patient was pathologically confirmed by trans-bronchial lung biopsy, another was preliminarily diagnosed using 18F-FDG PET/CT, then confirmed by postoperative histopathologic examination. Accordingly, previous studies showed that the common sources of endobronchial metastasis were from kidney, breast, and colorectal cancers (13)(14)(15). The results from our study and the previous publications suggested that we should pay more attention to the patients whose prior cancers were from kidney or rectum.…”

Section: Discussionsupporting

confidence: 51%

Clinical Characteristics of Patients With Solitary Pulmonary Mass After Radical Treatment for Primary Cancers: Pulmonary Metastasis or Second Primary Lung Cancer?

Gou

Chen

et al. 2013

Cancer Investigation

View full text Add to dashboard Cite

We identified clinical characteristics of 30 pulmonary metastasis (PM) patients and 29 second primary lung cancer (SPLC) patients with feature of solitary pulmonary mass (SPM) after radical treatment of prior cancers. 6.7% and 44.8% patients presented with centrally located SPM and the median event-free durations were 33 and 72 months in PM and SPLC groups, respectively. PM was more likely to be found in prior cancers with stage III. In conclusion, the location of SPM, the event-free duration and the prior tumor staging were important features for differentiating SPLC from PM among patients with SPM after prior cancers.

show abstract

Section: Discussionsupporting

confidence: 51%

Clinical Characteristics of Patients With Solitary Pulmonary Mass After Radical Treatment for Primary Cancers: Pulmonary Metastasis or Second Primary Lung Cancer?

Gou

Chen

et al. 2013

Cancer Investigation

View full text Add to dashboard Cite

show abstract

“…Atelectasis and visible tumors with hilar masses are common manifestations observed in the chest radiographs of patients with EBM 13,28. In our study, hilar mass, visible tumor and atelectasis were common findings, but 9.3% of patients had normal chest X-rays.…”

Section: Discussionmentioning

confidence: 43%

Endobronchial Metastases from Extrathoracic Malignancy

et al. 2013

View full text Add to dashboard Cite

PurposeEndobronchial metastasis is defined as documented extrathoracic malignancies metastatic to the endobronchus within a bronchoscopically visible range. Although the clinical and radiologic findings of endobronchial metastasis are similar to primary lung cancer, treatment and prognosis may be different. We hereby investigated the clinical, radiologic and bronchoscopic aspects of endobronchial metastases (EBM) in Korean patients.Materials and MethodsA total of 43 patients with EBM who underwent bronchoscopic biopsies from June 1991 to December 2009 at Severance Hospital, Yonsei University College of Medicine in Seoul, Korea, were analyzed retrospectively. We evaluated clinical, radiologic and bronchoscopic characteristics of EBM.ResultsThe patients consisted of 27 males and 16 females and their ages ranged from 18 to 77 years. The common primary cancers related to EBM were rectal (16.3%), colon (11.6%), breast (9.3%) and uterine (9.3%) cancers. The mean interval from diagnosis of primary cancer to EBM was 36 months, and the mean survival duration from diagnosis of EBM was 16.1 months in 33 deceased patients.ConclusionEBM develop in various types of malignancies at various times with unremarkable manifestations. Therefore, physicians should consider the possibility of EBM, especially if a patient has a history of any malignancy, regardless of respiratory symptoms. Respiratory symptoms related with EBM can be treated by various safe procedures.

show abstract

“…If bronchoscopy is performed before other examinations, thorax CT evaluation should be performed to detect other possible pulmonary metastases or hilar-mediastinal lymphadenopathies [3, 7,14,15,16]. In our series, CT revealed intraluminal lesions in 3 patients.…”

Section: Discussionmentioning

confidence: 98%

Endobronchial Metastases from Colorectal Adenocarcinomas: Clinical and Endoscopic Characteristics and Patient Prognosis

Díaz¹,

Fouchardière²,

Desseigne³

et al. 2007

Oncology

View full text Add to dashboard Cite

Background: Endobronchial metastases (EBM) secondary to extrapulmonary solid malignant tumours are rare but may occur. The most common extrathoracic malignancies associated with EBM are breast, renal and colorectal carcinomas. This study aimed to evaluate the clinical and bronchoscopic aspects of EBM from colorectal carcinomas and the prognosis of the patients. Methods: EBM were diagnosed in 7 patients with colorectal carcinomas between 2004 and 2005. All patients underwent colorectal resection at the time of primary tumour diagnosis. Bronchial involvement was proved by bronchoscopy, and the metastatic nature of the lesions was confirmed histopathologically in all patients. EBM patients were compared with a control group of 7 patients with pulmonary metastases from colorectal cancer. Results: Median age at time of colorectal carcinoma was 55 years in EBM patients and 57 years in controls. Distressing airway symptoms caused by EBM were relieved by use of newer intrabronchial therapies: radiotherapy, brachytherapy and cryotherapy. One patient underwent metastasis resection. The median survival after diagnosis of EBM was 18.9 months. All patients had pulmonary metastases. The median survival after diagnosis of pulmonary metastasis from colorectal carcinoma was 55.7 months in EBM patients and 12.7 months in controls (p < 0.005). Discussion: EBM are generally underdiagnosed in patients with colorectal carcinoma. Bronchoscopy is not part of the standard evaluation of these patients. Physicians must be more attentive to pulmonary symptoms, even when patients’ pulmonary metastases are known. Various management options are available for localized endobronchial tumours. Conclusion: On average, EBM are diagnosed about 5 years after the diagnosis of the primary tumour, which is a relatively long lead time. Although this metastatic location usually implies a very negative prognosis regarding life expectancy, it did not seem to significantly reduce survival in our patients. Local treatments allow substantial improvement of pulmonary symptoms.

show abstract

CT Findings of Endobronchial Metastasis

Cited by 20 publications

References 0 publications

Clinical Characteristics of Patients With Solitary Pulmonary Mass After Radical Treatment for Primary Cancers: Pulmonary Metastasis or Second Primary Lung Cancer?

Clinical Characteristics of Patients With Solitary Pulmonary Mass After Radical Treatment for Primary Cancers: Pulmonary Metastasis or Second Primary Lung Cancer?

Endobronchial Metastases from Extrathoracic Malignancy

Endobronchial Metastases from Colorectal Adenocarcinomas: Clinical and Endoscopic Characteristics and Patient Prognosis

Contact Info

Product

Resources

About