CT of acquired abnormalities of the spleen.

Taylor, Andrew; Dodds, W J; Erickson, S J; Stewart, Edward T.

doi:10.2214/ajr.157.6.1950868

Cited by 58 publications

(29 citation statements)

References 4 publications

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“…6,10,11,14,[24][25][26] In our study, no differences were seen between lymphoma and solid tumors according to the presence of other organ involvement. In other words, when we detected a splenic tumor, there were no differences between lymphoma and solid tumors regarding the presence of other organ involvement.…”

Section: 7contrasting

confidence: 66%

Splenic Malignant Lesions in Lymphoma and Solid Tumors, A Comparative Study of Imaging Techniques.

Ozen¹

2015

UHOD

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Splenic involvement guide treatment and affect prognosis in lymphoma and solid tumors. The most common used imaging techniques in detecting splenic involvement are Ultrasound (US) and Computed Tomography (CT). In this study, our aims were to evaluate the imaging findings regarding the spleen, compare splenic lesions according to the diagnosis and evaluate correlations between US and CT according to splenomegaly and lesions. Between May 2008 and April 2011 we identified 72 patients with splenic lesions or splenomegaly on CT or US. However, we exclude 27 patients from the study because of study protocol. Therefore, we enrolled 45 patients with a proven malignancy who had splenic lesions detected with CT. Seventeen patients had a diagnosis of lymphoma, and 28 patients had non-hematological malignancies. The characteristic features of the splenic lesions, detected on CT in patients with a proven malignancy, varied according to the cancer type. Multiple splenic lesions and splenomegaly in lymphoma patients and only solitary lesions in solid tumors were seen on CT (p< 0.001). Lymphoma patients usually had a solid splenic lesion with splenomegaly on US, but no lesion in solid tumors were seen on US (p< 0.05). The US and CT correlation ratio was inferior for solid tumors.US may miss splenic solid tumor metastases. CT is useful for distinguishing splenic lymphoma involvement from solid tumor metastases. CT seems superior to US in detecting splenic solid tumor metastases.Keywords: Spleen, Ultrasound, Computed Tomography, Lymphoma, Solid Malignancies ÖZET Lenfoma ve Solid Tümörlerde Dalağın Malign Lezyonları, Görüntüleme Teknikleri Kıyaslama ÇalışmasıLenfoma ve solid tümörlerde dalak tutulumu prognozu etkilemekte ve tedaviye klavuzluk etmektedir. Dalak tutulumunun tanımlanmasında en sık kullanılan görüntüleme teknikleri Ultrason (US) ve Bilgisayarlı Tomografi (BT)'dir. Bu çalışmada dalağın görüntüleme bulgularını değerlendirmeyi, tanıya göre dalak lezyonlarını kıyaslamayı ve splenomegali ve lezyonlara göre US ve BT arasındaki korelasyonu değerlendirmeyi amaçladık. Mayıs 2008 ve Nisan 2011 arasında BT veya US'de splenomegali veya dalak lezyonları olan 72 hasta tanımladık. Ancak, 27 hastayı çalışma protokolü nedeniyle çalışmadan çıkarttık. Sonuçta kanıtlanmış bir malignensisi olan ve BT ile dalakta lezyonu saptanmış 45 hastayı çalışmaya aldık. On yedi hastanın tanısı lenfoma, 28 hastanın tanısı ise hematolojik olmayan malignensi idi. Kanıtlanmış bir malignensisi olan hastalarda BT'de gözlenen dalak lezyonlarının karakteristik özel-likleri kanser tipine göre farklılık gösterdi. BT'de lenfoma hastalarında dalakta çok sayıda lezyonla birlikte splenomegali görülürken, solid tümörlerde yalnızca tek lezyon görüldü (p< 0.001). US'de lenfoma hastalarında genellikle bir solid lezyona eşlik eden splenomegali varken, solid tümörlerde US'de lezyon gözlenmedi (p< 0.05). US ve BT'nin korelasyon oranı solid tümörlerde düşüktü. US solid tümör metastazını gözden kaçırabilir. BT lenfomanın dalak tutulumunu solid tümörlerin dalak metas...

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Section: 7contrasting

confidence: 66%

Splenic Malignant Lesions in Lymphoma and Solid Tumors, A Comparative Study of Imaging Techniques.

Ozen¹

2015

UHOD

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“…(12) In contrast to accessory spleens, splenosis is an acquired condition secondary to seeding and implantation of splenic cells after splenic trauma or splenectomy. (7,13) As with accessory and ectopic spleens, such implants consist of functional splenic tissue, which provides some protection against infection. Usually the implants are multiple, measuring from a few millimetres up to several centimetres in diameter.…”

Section: Splenosismentioning

confidence: 99%

“…(2) In less typical cases, infarcts may mimic other splenic lesions, including abscesses or tumours, requiring clinical correlation, or if necessary, percutaneous fine-needle aspiration biopsy. (13) When the entire spleen is infarcted, it results in diffuse splenic hypodensity, leaving a residual rim of enhancing capsule supplied by small capsular vessels. This is known as the 'rim sign'.…”

Section: A 10b 10cmentioning

confidence: 99%

“…This is known as the 'rim sign'. (13) Chronic infarcts decrease in size, resulting in fibrotic retraction of the splenic capsule (Fig. 16).…”

Section: A 10b 10cmentioning

confidence: 99%

“…(3) The most common cause is portal hypertension, often associated with liver cirrhosis. (13) Different imaging modalities can be used to confirm splenomegaly and to search for extrasplenic manifestations of disease, providing clues to the correct cause. (1) Imaging may detect complications, including splenic rupture and infarction (Fig.…”

Section: Splenomegalymentioning

confidence: 99%

See 2 more Smart Citations

Imaging of the spleen: what the clinician needs to know

Vancauwenberghe¹,

Snoeckx²,

Vanbeckevoort³

et al. 2015

smedj

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The spleen is considered 'the forgotten organ' among radiologists and clinicians, although it is well visualised on abdominal computed tomography and magnetic resonance imaging. Moreover, the spleen is commonly involved in a wide range of pathologic disorders. These include congenital anomalies, infectious and inflammatory diseases, vascular disorders, benign and malignant tumours, and systemic disorders. In this review, we focus on the key imaging findings of the normal spleen, its variants, as well as relevant congenital and acquired abnormalities. It is of utmost importance to recognise and correctly interpret the variable spectrum of abnormalities that may involve the spleen, in order to avoid unnecessary invasive procedures and to guide adequate treatment.

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Normal and Benign Reactive Hematopoietic Tissues

Valli¹

2007

Veterinary Comparative Hematopathology

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CT of acquired abnormalities of the spleen.

Cited by 58 publications

References 4 publications

Splenic Malignant Lesions in Lymphoma and Solid Tumors, A Comparative Study of Imaging Techniques.

Splenic Malignant Lesions in Lymphoma and Solid Tumors, A Comparative Study of Imaging Techniques.

Imaging of the spleen: what the clinician needs to know

Normal and Benign Reactive Hematopoietic Tissues

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