CT of the liver: a survey of prevailing methods for administration of contrast material

Zeman, R K; Clements, LA; Silverman, P M; Dm, Paushter; Garra, Brian S.; Jaffe, M. J.; Lr, Clark

doi:10.2214/ajr.150.1.107

Cited by 28 publications

(6 citation statements)

References 6 publications

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“…AJR 1995;164:327-331 Much has been written about the optimal temporal window for dynamic incremental bolus contrast-enhanced CT of the liver [1][2][3][4][5][6][7][8][9][10][11][12][13][14].…”

Section: Discussionmentioning

confidence: 99%

Use of contrast material for spiral CT of the abdomen: comparison of hepatic enhancement and vascular attenuation for three different contrast media at two different delay times.

Herts¹,

Paushter²,

Einstein³

et al. 1995

American Journal of Roentgenology

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OBJECTIVE.The purpose of this study was to determine the relative effects of delay time, contrast agent concentration, and contrast agent volume on hepatic enhancement and on sortie and portal vein attenuation for contrast-enhanced spiral CT of the abdomen. The effect of delay time was evaluated by comparing two different delay times for each of three IV contrast media. Three different media were tested to CONCLUSION.When IV contrast material was Injected with a low-flow-rate monophasic bolus, a delay time of 60 see, longer than that typically used for dynamic incremental scanning, provided greater hepatic enhancement in spiral CT. This result was significant for the three contrast media tested. Aortlc attenuation was significantly greater at shorter delay tImes when a smaller volume of contrast material was injected. Portal vein attenuation was greater at longer delay times, suggesting that the optimal delay time may be longer than 60 sec. Further work to determine the optimal scanning window for hepatic enhancement in spiral CT by use of time-density curves is Indicated.

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Section: Discussionmentioning

confidence: 99%

Use of contrast material for spiral CT of the abdomen: comparison of hepatic enhancement and vascular attenuation for three different contrast media at two different delay times.

Herts¹,

Paushter²,

Einstein³

et al. 1995

American Journal of Roentgenology

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“…The CM are generally given as a bolus injection before imaging. If slow scanners are used, they may be supplemented with an injection during the examination (24). This method is normally referred to as dynamic CT or dynamic incremental CT (DICT).…”

Section: Discussionmentioning

confidence: 99%

A New Liposomal Contrast Medium for CT of the Liver

Leander¹

1996

Acta Radiol

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A new type of liposomal liver-specific contrast medium was studied in an experimental tumour model. Rabbits were inoculated with VX2-carcinoma directly into the liver at laparotomy. CT studies were carried out 14 days after inoculation. The liverspecific contrast medium consisted of a suspension of liposomes in a 100 mg I/ml iodixanol solution, with equal amounts of encapsulated and nonencapsulated iodixanol. It was administered at a dose of 200 mg Ukg. The contrast of normal liver tissue to tumorous tissue was significantly increased by contrast medium administration. the increase being largest 10 min after injection.

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“…CT with bolus IV contrast enhancement and dynamic scanning techniques is widely used for the detection of focal liver lesions [1]. On contrast-enhanced CT, abnormalities of hepatic attenuation may also be produced by hemodynamic disturbances, such as hepatic venous thrombosis, which affect the delivery of contrast material to the liver [2,3].…”

Section: Ancillarymentioning

confidence: 99%