CT-Volumetrie der Leber vor Transplantation

Lemke, A.-J.; Hosten, Norbert; Neumann, K.; Müller, B.S.; Félix, R.; Langer, R

doi:10.1055/s-2007-1015371

Cited by 34 publications

(29 citation statements)

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“…One reason is the loss of liver blood volume after dissection of the vessels. Another reason is that the mean specific gravity of healthy liver tissue is considered to be 1.00 g/mL so that preoperatively calculated volumes of the liver and both of its lobes are approximately equal to their respective weights [24,49]. A change in liver density to only 1.05 g/mL would account for a 5% difference.…”

Section: Discussionmentioning

confidence: 99%

Exact CT-Based Liver Volume Calculation Including Nonmetabolic Liver Tissue in Three-Dimensional Liver Reconstruction

Müller

Bläuer

Kremer

et al. 2010

Journal of Surgical Research

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Section: Discussionmentioning

confidence: 99%

Exact CT-Based Liver Volume Calculation Including Nonmetabolic Liver Tissue in Three-Dimensional Liver Reconstruction

Müller

Bläuer

Kremer

et al. 2010

Journal of Surgical Research

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“…Volume calculations using conventional and helical CT are reported to be relatively accurate [24,[35][36][37]. It is widely assumed that the mean specific gravity of healthy liver tissue is 1.00 g/ml so that preoperatively calculated volumes of the entire living donor's liver and both of its lobes are approximately equal to their respective weights [38,39].…”

Section: Liver Volumementioning

confidence: 99%

Partial liver transplantation-living donor liver transplantation and split liver transplantation

Müller

Mehrabi

Schmied

et al. 2007

Nephrology Dialysis Transplantation

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In the last two decades, liver transplantation (LTx) has become the treatment of choice for several liver diseases including hepatocellular carcinoma in selected cases. Improvements in surgical and anesthesiological procedures have increased patient survival after LTx, resulting in excellent 1-year survival rates. The ratelimiting factor to further increase the number of LTx is the extreme shortage of suitable organs with the consequence that pediatric and adult patients are dying on the waiting list. At present, mortality reported for pediatric and adult patients on the waiting list is 10 to 20%. Living-donor liver transplantation and split liver transplantation are measurements to reduce the severe lack of cadaveric grafts by expanding the donor pool. Major centers around the world now routinely perform partial LTx in infants and adults with survival success equivalent to that after full-size liver transplantation.

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“…Lemke et al found densities between 0.67 g/cm³ and 1.66 g/cm³ [17]. Volumes measured by water displacement in the present study cannot be compared to volumes found in the literature, because we only measured resected liver parts which differ a lot in size, because different segments were resected in every case.…”

Section: Resected Liver Volumementioning

confidence: 66%

“…Some studies concerning liver volumetry used explanted livers to measure the real total liver volume [8,17] but in these studies no measurement of resected liver parts was possible. In the clinical routine it is very important to get a realistic estimate of resected and remaining liver parts for both hemihepatectomy and living-donor liver transplantation.…”

Section: Limitationsmentioning

confidence: 99%

Validating New Software for Semiautomated Liver Volumetry – Better than Manual Measurement?

Noschinski

Maiwald

Voigt

et al. 2015

Fortschr Röntgenstr

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!Purpose: This prospective study compared a manual program for liver volumetry with semiautomated software. The hypothesis was that the semiautomated software would be faster, more accurate and less dependent on the evaluator's experience. Materials and Methods: Ten patients undergoing hemihepatectomy were included in this IRB approved study after written informed consent. All patients underwent a preoperative abdominal 3-phase CT scan, which was used for whole liver volumetry and volume prediction for the liver part to be resected. Two different types of software were used: 1) manual method: borders of the liver had to be defined per slice by the user; 2) semiautomated software: automatic identification of liver volume with manual assistance for definition of Couinaud segments. Measurements were done by six observers with different experience levels. Water displacement volumetry immediately after partial liver resection served as the gold standard. The resected part was examined with a CT scan after displacement volumetry. Results: Volumetry of the resected liver scan showed excellent correlation to water displacement volumetry (manual: ρ = 0.997; semiautomated software: ρ = 0.995). The difference between the predicted volume and the real volume was significantly smaller with the semiautomated software than with the manual method (33 % vs. 57 %, p = 0.002). The semiautomated software was almost four times faster for volumetry of the whole liver (manual: 6:59 ± 3:04min; semiautomated: 1:47 ± 1:11 min). Conclusion: Both methods for liver volumetry give an estimated liver volume close to the real one. The tested semiautomated software is faster, more accurate in predicting the volume of the resected liver part, gives more reproducible results and is less dependent on the user's experience.This document was downloaded for personal use only. Unauthorized distribution is strictly prohibited.

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CT-Volumetrie der Leber vor Transplantation

Abstract: In conclusion, both incremental CT and spiral CT are reliable methods for the preoperative estimation of the liver volume, whereas best accordance with the corrected water displacement volume was obtained using the individual segmentation thresholds.

Cited by 34 publications

References 0 publications

Exact CT-Based Liver Volume Calculation Including Nonmetabolic Liver Tissue in Three-Dimensional Liver Reconstruction

Exact CT-Based Liver Volume Calculation Including Nonmetabolic Liver Tissue in Three-Dimensional Liver Reconstruction

Partial liver transplantation-living donor liver transplantation and split liver transplantation

Validating New Software for Semiautomated Liver Volumetry – Better than Manual Measurement?

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