Cu(i)-catalysed 1,2,3-triazole stitched chalcomer assembly as Pb(ii) and Cu(ii) ion sensor: DFT and docking scrutiny

Abstract

1,2,3-triazole derivative (CBT) was synthesized using the CuAAC procedure, with chalcone skeleton and was implemented as an effective sensor for Pb(ii) and Cu(ii) ions.

Unveiling the ion sensing capabailities of ‘click’ derived chalcone-tailored 1,2,3-triazolic isomers for Pb(ii) and Cu(ii) ions: DFT analysis

“…For synthetic chemists, using CuAAC to design selective 1,2,3-triazole-based chemosensors can be beneficial due to the method's selectivity, simplicity of experimental setup, tolerance of a broad range of functional groups, and high quantitative yields. 20 Traditional analytical methods for sensing metal ions, such as atomic absorption spectrometry (AAS) 21 and inductively coupled plasma mass spectrometry (ICPMS) 22 are used for sensing metal ions, however, despite their high sensitivity, they are not suitable for on-site investigation owing to their costly instrumentation, extensive set-up time in specialized laboratories, and strenuous sample preparation. 23 …”