Cu^I-amidobis(phosphine) catalyzed C(sp³)–C(sp³) direct homo- and hetero-coupling of unactivated alkanes via C(sp³)–H activation

Abstract

Herein, we present the CuI-dimer, [CuI{Ph2PC6H4C(O)NC6H4PPh2-o}]2 catalyzed direct C(sp3)‒H homocoupling of benzyl and cycloalkane derivatives with excellent yields and regio-selectivity. The method is very simple and tolerates various functionalities. Synergistic...