Cu2O nanocubes–grafted highly dense Au nanoparticles with modulated electronic structures for improving peroxidase catalytic performances

Jiao, Anxin; Xu, Linlin; Tian, Yue; Cui, Qingqiang; Liu, Xiangdong; Chen, Ming

doi:10.1016/j.talanta.2020.121990

Cited by 41 publications

(25 citation statements)

References 64 publications

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“…The optimal pH was first investigated since pH had a significant effect on the activity of mimetic peroxidase. The activity of Cu 2 O-based peroxidase was higher under acidic conditions and weaker under alkaline conditions. , Therefore, HAc-NaAc solutions with different pHs (3–12) were prepared and used as the diluent of H 2 O 2 for the further catalytic reaction with 4-CN. As shown in Figure A,B, τ showed the maximum value when the pH was 3 and 4 and gradually decreased as the pH increased.…”

Section: Resultsmentioning

confidence: 99%

Handheld Platform for Sensitive Rosiglitazone Detection: Immunosensor Based on a Time-Based Readout Device

et al. 2022

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The detection of rosiglitazone (RSG) in food is of great importance since the excessive intake of RSG could cause adverse effects on the human body. Although liquid chromatography–mass spectrometry and gas chromatography–mass spectrometry are the preliminary methods for the detection of hazardous materials in food, they are not suitable for point-of-care or on-site detection. Herein, a time-based readout (TBR) device with an application software (APP) controlled by a smart phone was developed for the sensitive and selective immunoassay of RSG. The homemade TBR device was based on a two-electrode system, where the immune molecule-modified glassy carbon electrode was used as the bioanode, and Prussian blue-modified FTO was used as the cathode. By using Au-modified octahedral Cu2O with high catalytic activity as mimetic peroxidase, an insulating layer was generated on the cathode by catalyzing 4-chloro-1-naphthol (4-CN) into benzo-4-chlorohexadienone (B4Q). The time to reach a fixed potential varied indirectly with the concentrations of RSG and was recognized by the APP, while the electrochromic property on the cathode was also correspondingly changed. Under optimum conditions, both the square root of the time and the chroma value of the electrochromism exhibited linear responses for the detection of RSG ranging from 5 × 10–10 to 5 × 10–7 g/L, while the limits of detection were 8.2 × 10–11 and 1.3 × 10–10 g/L, respectively. With easy operation and portability, this TBR device showed a promising application for point-of-care monitoring of hazardous materials in food or the environment.

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Section: Resultsmentioning

confidence: 99%

Handheld Platform for Sensitive Rosiglitazone Detection: Immunosensor Based on a Time-Based Readout Device

et al. 2022

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“…Up to now, nanozymes with enzyme-mimicking characteristics have attracted tremendous attention in antibacterial therapy due to their excellent biocompatibility, tunable activity, long-term storage, ease for multifunctionalization, and rapid antimicrobial effect. − The mimicking of peroxidase (POD)-like activities by nanozymes can catalyze the decomposition of hydrogen peroxide (H 2 O 2 ) with low doses into oxidizing reactive oxygen species (ROS) including hydroxyl radicals ( · OH) and superoxide anions ( · O 2 – ) with strong oxidizing properties, , which is an effective strategy to improve the antibacterial efficiency, maintain low toxicity, and save energy. Diverse nanozymes with POD-like activities have emerged, such as noble metals, transition metals, − and carbon-nanostructured materials and their oxides. ,,, For instance, Jiao et al grafted Cu 2 O nanocubes onto high-density gold nanoparticles as an attractive nanozyme for H 2 O 2 colorimetric sensors and antioxidant detection, achieving a high POD-like activity . Although the POD-like activities of the current nanozymes have been greatly improved, it remains a challenge to develop POD-like nanozymes with low cost, high yield, and good stability for antibacterial properties against bacteria.…”

Section: Introductionmentioning

confidence: 99%

Attapulgite Doped with Fe and Cu Nanooxides as Peroxidase Nanozymes for Antibacterial Coatings

Feng

Zhang

et al. 2022

ACS Appl. Nano Mater.

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The search for low-cost, highly efficient, and stable nanozymes mimicking peroxidase (POD) enzymes remains a great challenge in the development of valuable antibacterial applications. Herein, a natural attapulgite (ATP)-supported Fe and Cu oxide with mixed valences (Fe-Cu/ATP) is reported as an efficient nanozyme by a feasible impregnation method. The obtained Fe-Cu/ATP nanozyme with a large specific area and high dispersity can effectively catalyze the hydrogen peroxide (H 2 O 2 ) decomposition, exhibiting enhanced POD-like activity compared with Fe/ATP, Cu/ATP, and pristine ATP. In addition, the Fe-Cu/ATP showed high stability and reusability. Through further combination with the density functional theory calculation, the electron density of the ATP surface is increased by simultaneously introducing Fe and Cu dopants. Thus, Fe-Cu/ATP possesses excellent antibacterial properties including a short-time effect depending on the POD-like activity with H 2 O 2 and a long-term effect generated by the metal without H 2 O 2 . Finally, a coating desktop and an antibacterial fabric were delicately designed and fabricated by loading Fe-Cu/ATP onto polyethylene and a fabric surface, showing the enormous potential of Fe-Cu/ATP as building and medical functional coatings. This study provides a rational way to design natural mineral nanozymes for promising antibacterial applications.

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“…A variety of substances with peroxidase-like properties sprung up like mushrooms, from noble metal nanoparticles [ 6 ], metal oxides [ 7 ], to multi-metal compounds [ 8 ]. This peroxidase-like activity of nanozymes has been used in colorimetry to detect many biologically related substances, such as H 2 O 2 [ 9 ], glucose [ 10 ], DA [ 11 ], and glutathione [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Peroxidase-Like Platinum Clusters Synthesized by Ganoderma lucidum Polysaccharide for Sensitively Colorimetric Detection of Dopamine

et al. 2021

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The sensitive and selective detection of dopamine (DA) is very important for the early diagnosis of DA-related diseases. In this study, we reported the colorimetric detection of DA using Ganoderma lucidum polysaccharide (GLP) stabilized platinum nanoclusters (Ptn-GLP NCs). When Pt600-GLP NCs was added, 3,3’,5,5’-tetramethylbenzidine (TMB) was rapidly catalyzed and oxidized to blue oxTMB, indicating the peroxidase-like activity of Pt600-GLP NCs. The catalytic reaction on the substrate TMB followed the Michaelis-Menton kinetics with the ping-pong mechanism. The mechanism of the colorimetric reaction was mainly due to the formation of hydroxyl radical (•OH). Furthermore, the catalytic reaction of Pt600-GLP NCs was used in the colorimetric detection of DA. The linear range for DA was 1–100 μM and the detection limit was 0.66 μM. The sensitive detection of DA using Pt-GLP NCs with peroxidase-like activity offers a simple and practical method that may have great potential applications in the biotechnology field.

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Cu2O nanocubes–grafted highly dense Au nanoparticles with modulated electronic structures for improving peroxidase catalytic performances

Cited by 41 publications

References 64 publications

Handheld Platform for Sensitive Rosiglitazone Detection: Immunosensor Based on a Time-Based Readout Device

Handheld Platform for Sensitive Rosiglitazone Detection: Immunosensor Based on a Time-Based Readout Device

Attapulgite Doped with Fe and Cu Nanooxides as Peroxidase Nanozymes for Antibacterial Coatings

Peroxidase-Like Platinum Clusters Synthesized by Ganoderma lucidum Polysaccharide for Sensitively Colorimetric Detection of Dopamine

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