2024
DOI: 10.1021/acsapm.4c00571
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Cucurbituril-Based Porphyrin Cascade Assembly for Cell Imaging and Targeted Drug Delivery

Xing Yuan,
De-Fang Xu,
Yahui Song
et al.

Abstract: Supramolecular assemblies based on multiple host−guest interactions have aroused widespread interest in the fabrication of innovative biomaterials. In this work, a combinational nanosupramolecule is constructed by an orthogonal two-step self-assembling process. The generation efficiency of reactive oxygen species and fluorescence emission intensity of pyridiniumappended porphyrin are greatly enhanced upon inclusion complexation with cucurbit[8]uril. Meanwhile, the introduction of β-cyclodextrin-grafted hyaluro… Show more

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