Cuffless Single-Site Photoplethysmography for Blood Pressure Monitoring

Hosanee, Manish; Chan, Gabriel; Welykholowa, Kaylie; Cooper, Rachel; Kyriacou, Panayiotis A.; Zheng, Dingchang; Allen, John; Abbott, Derek; Menon, Carlo; Lovell, Nigel H.; Howard, Newton; Chan, Wee-Shian; Lim, Kenneth; Fletcher, Roger; Ward, Rabab; Elgendi, Mohamed

doi:10.3390/jcm9030723

Cited by 107 publications

(68 citation statements)

References 36 publications

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“…This has most commonly been measured using PPG as it has the ability to detect changes in blood pulsation through monitoring the variation in light absorption from a photodetector placed near a light-emitting diode [7]. Further details regarding the extraction of specific feature(s) from a single PPG signal and how these features can be incorporated into BP estimations are discussed and examined in our previous work [4,6,[8][9][10]. This review focuses on evaluating various PPG-based multimodal biosignal systems that have been investigated by researchers in an attempt to estimate BP and assess hypertension.…”

Section: Introductionmentioning

confidence: 99%

Multimodal Photoplethysmography-Based Approaches for Improved Detection of Hypertension

Welykholowa

Hosanee

Chan

et al. 2020

JCM

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Elevated blood pressure (BP) is a major cause of death, yet hypertension commonly goes undetected. Owing to its nature, it is typically asymptomatic until later in its progression when the vessel or organ structure has already been compromised. Therefore, noninvasive and continuous BP measurement methods are needed to ensure appropriate diagnosis and early management before hypertension leads to irreversible complications. Photoplethysmography (PPG) is a noninvasive technology with waveform morphologies similar to that of arterial BP waveforms, therefore attracting interest regarding its usability in BP estimation. In recent years, wearable devices incorporating PPG sensors have been proposed to improve the early diagnosis and management of hypertension. Additionally, the need for improved accuracy and convenience has led to the development of devices that incorporate multiple different biosignals with PPG. Through the addition of modalities such as an electrocardiogram, a final measure of the pulse wave velocity is derived, which has been proved to be inversely correlated to BP and to yield accurate estimations. This paper reviews and summarizes recent studies within the period 2010–2019 that combined PPG with other biosignals and offers perspectives on the strengths and weaknesses of current developments to guide future advancements in BP measurement. Our literature review reveals promising measurement accuracies and we comment on the effective combinations of modalities and success of this technology.

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Section: Introductionmentioning

confidence: 99%

Multimodal Photoplethysmography-Based Approaches for Improved Detection of Hypertension

Welykholowa

Hosanee

Chan

et al. 2020

JCM

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“…PPG is usually measured at body extremities, such as fingers, ears, and wrists 4 . It provides valuable physiological and pathological information about the cardiovascular system.…”

Section: Introductionmentioning

confidence: 99%

Synthetic photoplethysmogram generation using two Gaussian functions

Tang

Chen

Ward

et al. 2020

Sci Rep

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Evaluating the performance of photoplethysmogram (PPG) event detection algorithms requires a large number of PPG signals with different noise levels and sampling frequencies. As publicly available PPG databases provide few options, artificially constructed PPG signals can also be used to facilitate this evaluation. Here, we propose a dynamic model to synthesize PPG over specified time durations and sampling frequencies. In this model, a single pulse was simulated by two Gaussian functions. Additionally, the beat-to-beat intervals were simulated using a normal distribution with a specific mean value and a specific standard deviation value. To add periodicity and to generate a complete signal, the circular motion principle was used. We synthesized three classes of pulses by emulating three different templates: excellent (systolic and diastolic waves are salient), acceptable (systolic and diastolic waves are not salient), and unfit (systolic and diastolic waves are noisy). The optimized model fitting of the Gaussian functions to the templates yielded 0.99, 0.98, and 0.85 correlations between the template and synthetic pulses for the excellent, acceptable, and unfit classes, respectively, with mean square errors of 0.001, 0.003, and 0.017, respectively. By comparing the heart rate variability of real PPG and randomly synthesized PPG for 5 min in 116 records from the MIMIC III database, strong correlations were found in SDNN,

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“…However, these works [16], [17] are more focused on cNIBP's feasibility for telemonitoring, revealing challenges this technology needs to overcome in order to apply it to practical scenarios. Besides, cNIBP based on photoplethysmogram (PPG) has gained great interest as several papers [12], [18], [19] solely review this method. For instance, Wang and colleagues [18] intuitively provide PPG sensing principles of operation, PPG sensor circuit configurations for BP measurement, as well as different BP models and algorithms for calculating BP values.…”

Section: Introductionmentioning

confidence: 99%

“…For instance, Wang and colleagues [18] intuitively provide PPG sensing principles of operation, PPG sensor circuit configurations for BP measurement, as well as different BP models and algorithms for calculating BP values. Single-site and multi-site PPG technologies are reviewed in [12], [19], which provides audience a broad overview on the use of PPG to derive BP. All those review papers show the theoretical exploration and potential approaches of cNIBP.…”

Section: Introductionmentioning

confidence: 99%

Continuous Non-Invasive Blood Pressure Monitoring: A Methodological Review on Measurement Techniques

Ellington

Lee

et al. 2020

IEEE Access

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Continuous measurement of blood pressure is crucial to the assessment of many medical conditions. However, the current clinical gold standard involving an arterial catheter, occluding cuff, and other invasive procedures are performed in hospital settings while home-based devices can provide only intermittent measurement and are not as reliable. Therefore, there is a significant need for continuous noninvasive blood pressure (cNIBP) monitoring in the daily life. Pulse transit time (PTT)/pulse arrival time (PAT)-based blood pressure measurement has proven its potential to address this need. In this article, we present state-of-the-art devices and recent literature related to measurement technologies used in PTT/PAT-based methods for cNIBP monitoring. Various physiological signals which could be used to enable cNIBP in the home setting are categorized into two groups (i.e., proximal waveforms and distal waveforms) and are thoroughly discussed and compared. Given insightful analysis of these waveforms, we highlight their combinations to derive PTT/PAT values for BP measurement then discuss challenges presented from the cuffless and PTT/PAT-based nature of these devices. Finally, we conclude with future directions needed for home-based cNIBP adaptation and present societal broader impacts.

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Cuffless Single-Site Photoplethysmography for Blood Pressure Monitoring

Cited by 107 publications

References 36 publications

Multimodal Photoplethysmography-Based Approaches for Improved Detection of Hypertension

Multimodal Photoplethysmography-Based Approaches for Improved Detection of Hypertension

Synthetic photoplethysmogram generation using two Gaussian functions

Continuous Non-Invasive Blood Pressure Monitoring: A Methodological Review on Measurement Techniques

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