cular events in patients with acute coronary syndrome (ACS). 5 Interventional studies also failed to find a protective effect of continuous positive airway pressure (CPAP) treatment on the recurrence of coronary artery disease (CAD) or ACS, 6,7 emphasizing the need to better identify high-risk subsets of ACS patients.Coronary revascularization is the most effective treatment for CAD, but residual angina or recurrent cardiac event after revascularization is not uncommon. 8-10 OSA was reported as a risk factor for recurrent events after percutaneous coronary intervention (PCI). 11-13 However, the Sleep and Stent Study found no significant difference O bstructive sleep apnea (OSA) is characterized by frequent partial or complete closure of the upper airway during sleep. 1 OSA is associated with increased risk of cardiovascular disease, but it remains uncertain whether OSA increases recurrent cardiovascular events. 2 Several longitudinal observational studies reported that OSA was an independent predictor of poor outcomes in patients with known cardiovascular diseases. 3,4 However, the Impact of Sleep Apnea Syndrome in the Evolution of Acute Coronary Syndrome/Effect of Intervention With Continuous Positive Airway Pressure (ISAACC) study reported that OSA does not increase the risk of cardiovas-