Despite the abundance of studies investigating the benefits of having a dog, the specific aspects of dog ownership that impacts human well-being are not well understood. This study used a qualitative approach to create a framework of the main dog-related activities perceived by Brazilian owners to impact their well-being and compared the findings with those of a similar study in England. Thirty-two Brazilian dog owners from the five regions of the country were remotely interviewed. The thematic analysis of the transcripts generated a total of 58 dog-related activities, organised into 13 themes. Most activities were reported to have a positive effect on participants’ well-being, accounting for 76.8% of the total number of mentions in the interviews. ‘Playing with dog’ and ‘Dog presence’ were the themes most frequently associated with positive well-being outcomes, whereas ‘Unwanted behaviours’ and ‘Failing to meet dog's needs’ were the most commonly associated with negative outcomes. The dog-related activities reported by Brazilian dog owners and the well-being outcomes linked to those activities were consistent with the previous British sample in the framework that emerged. These findings suggest reliability between the two methods used to gather data (remote interview versus focus group) and, most importantly, provide consistent cross-cultural evidence for how certain activities impact dog owner’s well-being.