The constant changes in the Life Orientation (LO) curriculum in the past two decades has left LO teachers feeling overwhelmed by the complex nature of the subject, thus necessitating an urgent need for their development and enrichment. However, this has become a mammoth task, as indicated in the few studies that have explored LO teachers' career development needs. This article seeks to narrow this gap by addressing the career development needs of LO teachers in the Gauteng Province with the view of enabling them to effectively implement the Life Orientation curriculum. This article is based on a study that employed a qualitative design, which comprised individual and focus group interviews to elicit responses from a purposively selected group of LO teachers. Themes that emerged from the data analysis are, the need for formal training, the need for subject and content knowledge development, the need for support from key stakeholders, the need for resources, and the need for stability in the LO subject. These needs are embedded within the activity theory (AT). The results of this study indicate that an urgency exists to address the LO teachers' career needs in the constantly changing world of work.